PROFESSIONAL EXPERIENCES
2016.06 – Current Post-doc, Dept. Systems Biotechnology, Konkuk University
2014.07 – 2016.05 Post-doc, Biochemicals & Synthetic Biology Research Center, KRIBB
2008.03 – 2014.02 Teaching Assistant, Department of Life Science, Korea University
EDUCATIONAL BACKGROUND
2014.02 Department of Life Science, Korea University (Ph.D.)
(Thesis: RaoN, a Novel Non-coding RNA, Induces Resistance to Macrophage-Related Stresses in Salmonella, Professor: Yong-Keun Park)
2008.02 Department of Biotechnology and Bioinformatics, Korea University (B.S.)
RESEARCH INTERESTS
Systems Biology
Molecular Biology
Microbiology
AWARDS
2017.04 Outstanding Poster, International Meeting of Microbiological Society of Korea
2011.10 Outstanding Poster, International Meeting of the Federation of Korean Microbiological Societies
PUBLICATIONS AND PATENTS
1) Kim S, Kim Y, Suh DH, Lee CH, Yoo SM, Lee SY, and Yoon SH “Heat-responsive and time-resolved transcriptome and metabolome analyses of Escherichia coli uncover thermo-tolerant mechanisms” Scientific Reports 10(1):17715 (2020.10)
2) Kim H, Kim S, Kim D, and Yoon SH “A single amino acid substitution in aromatic hydroxylase (HpaB) of Escherichia coli alters substrate specificity of the structural isomers of hydroxyphenylacetate” BMC Microbiology 20:109 (2020.05)
3) Jeong H, Lee S-W, Kim SH, Kim E-Y, Kim S, and Yoon SH “Global functional analysis of butanol-sensitive Escherichia coli and its evolved butanol-tolerant strain” J. Microbiol. Biotechnol. 27(6):1171–1179 (2017.06)
4) Kim S, Jeong H, Kim E-Y, Kim JF, Lee SY, and Yoon SH “Genomic and transcriptomic landscape of Escherichia coli BL21(DE3)” Nucleic Acids Res. 45(9): 5285-5293 (2017.05)
5) Yoon WS, Kim S, Seob S, Park YK. “Salmonella typhimurium with γ-radiation induced H2AX phosphorylation and apoptosis in melanoma.” Bioscience, Biotechnology, and Biochemistry. (2014;78(6):1082-5)
6) Yoon W, Choi JH, Kim S, Park YK. Engineered Salmonella typhimurium expressing E7 fusion protein, derived from human papillomavirus, inhibits tumor growth in cervical tumor-bearing mice. Biotechnol Lett. (2014 Feb;36(2):349-56).
7) Lee YH*, Kim S*, Helmann JD, Kim BH, Park YK. “RaoN, a Small RNA Encoded within Salmonella Pathogenicity Island-11, Confers Resistance to Macrophage-Induced Stress.” Microbiology. (2013 Jul;159(Pt 7):1366-78). *co-first authors
8) Lee YH*, Kim S*, Kim JH, Bang IS, Lee IS, Bang SH, Park YK. “A phosphotransferase system permease is a novel component of CadC signaling in Salmonella enterica.” FEMS Microbiol Lett. (2013 Jan;338(1):54-61). *co-first authors
9) 윤성호, 김신연 “YbeD 단백질을 과발현하는 고온 내성 미생물 및 이를 이용한 고온 내성 미생물의 배양 방법” (특허출원: 10-2018-0009345, 2018.01.25)
10) 박용근, 윤원석, 김신연 "스펙티노마이신 저항성 유전자를 발현하는 벡터를 포함하는 살모넬라 및 이를 이용한 살모넬라 약독화 방법" (특허출원: 10-2013-0060851, 2013.05.29)
