NZ_ADVE02000003.1 - 2 clusters

Identified secondary metabolite clusters

Cluster	Type	From	To	Most similar known cluster	MIBiG BGC-ID
The following clusters are from record NZ_ADVE02000003.1:
Cluster 1	Nrps-T1pks	7574	81180	Pyoverdine_biosynthetic_gene_cluster (9% of genes show similarity)	BGC0000413_c1
Cluster 2	T1pks	97005	152055	Neocarzilin_biosynthetic_gene_cluster (28% of genes show similarity)	BGC0000111_c1

NZ_ADVE02000003 - Cluster 1 - Nrps-t1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:: (pk-lys) + (ohmal) + (nrp) + (nrp-nrp) + (gly) + (asp-thr-nrp)
METTRDRAFT_RS0223355: NRPSPredictor2 SVM: asp; Stachelhaus code: asp; Minowa: asp; consensus: asp; NRPSPredictor2 SVM: thr; Stachelhaus code: thr; Minowa: thr; consensus: thr; NRPSPredictor2 SVM: glu,gln; Stachelhaus code: thr; Minowa: ser; consensus: nrp; Search NORINE for peptide in strict mode // relaxed mode
METTRDRAFT_RS0223365: NRPSPredictor2 SVM: gly; Stachelhaus code: gly; Minowa: gly; consensus: gly; Search NORINE for peptide in strict mode // relaxed mode
METTRDRAFT_RS0223370: NRPSPredictor2 SVM: glu,gln; Stachelhaus code: thr; Minowa: ser; consensus: nrp; NRPSPredictor2 SVM: hydrophilic; Stachelhaus code: ser; Minowa: dab; consensus: nrp; Search NORINE for peptide in strict mode // relaxed mode
METTRDRAFT_RS0223375: NRPSPredictor2 SVM: glu,gln; Stachelhaus code: thr; Minowa: ser; consensus: nrp; Search NORINE for peptide in strict mode // relaxed mode
METTRDRAFT_RS0223380: PKS signature: mal; Minowa: mal; consensus: ohmal
METTRDRAFT_RS0223385: Minowa: NH2; NRPSPredictor2 SVM: asp,asn,glu,gln,aad; Stachelhaus code: lys; Minowa: lys; consensus: lys; Search NORINE for peptide in strict mode // relaxed mode

Database cross-links

Link to NORINE database query form
Direct lookup in NORINE database in strict mode // relaxed mode

Gene cluster description

Download cluster GenBank file

NZ_ADVE02000003 - Gene Cluster 1. Type = nrps-t1pks. Location: 7574 - 81180 nt. Click on genes for more information.

Show pHMM detection rules used

nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes

transport-related genes

regulatory genes

other genes

Detailed annotation

Homologous gene clusters

Homologous known gene clusters

NZ_ADVE02000003 - Cluster 2 - T1pks