Identified secondary metabolite clusters

Cluster Type From To Most similar known cluster MIBiG BGC-ID
The following clusters are from record NZ_ADVE02000001.1:
Cluster 1Terpene900329896--
Cluster 2Bacteriocin852984863832--
Cluster 3Nrps14133071466419Polyhydroxyalkanoate_biosynthetic_gene_cluster (50% of genes show similarity)BGC0000866_c1
Cluster 4Terpene15575021579469--
Cluster 5Nrps22611782342632Lysobactin_biosynthetic_gene_cluster (4% of genes show similarity)BGC0000385_c1
Cluster 6Other25718652614669--
Cluster 7Terpene27096832755892--
Cluster 8Other34140143456908Cupriachelin_biosynthetic_gene_cluster (17% of genes show similarity)BGC0000330_c1

NZ_ADVE02000001 - Cluster 1 - Terpene

Gene cluster description

Download cluster GenBank file
NZ_ADVE02000001 - Gene Cluster 1. Type = terpene. Location: 9003 - 29896 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

NZ_ADVE02000001 - Cluster 2 - Bacteriocin

Gene cluster description

Download cluster GenBank file
NZ_ADVE02000001 - Gene Cluster 2. Type = bacteriocin. Location: 852984 - 863832 nt. Click on genes for more information.
Show pHMM detection rules used
bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Bacteriocin_Iii or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03605 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03882 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

NZ_ADVE02000001 - Cluster 3 - Nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(pk-his-nrp-nrp) + (mal)
METTRDRAFT_RS0207030
PKS signature: mal
Minowa: mal
consensus: mal

METTRDRAFT_RS0207040
Minowa: NH2

NRPSPredictor2 SVM: val,leu,ile,abu,iva
Stachelhaus code: his
Minowa: his
consensus: his

NRPSPredictor2 SVM: N/A
Stachelhaus code: ser
Minowa: dab
consensus: nrp

NRPSPredictor2 SVM: N/A
Stachelhaus code: ser
Minowa: dab
consensus: nrp

Search NORINE for peptide in strict mode // relaxed mode

Database cross-links

Link to NORINE database query form
Direct lookup in NORINE database in strict mode // relaxed mode

Gene cluster description

Download cluster GenBank file
NZ_ADVE02000001 - Gene Cluster 3. Type = nrps. Location: 1413307 - 1466419 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Homologous known gene clusters

NZ_ADVE02000001 - Cluster 4 - Terpene

Gene cluster description

Download cluster GenBank file
NZ_ADVE02000001 - Gene Cluster 4. Type = terpene. Location: 1557502 - 1579469 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

NZ_ADVE02000001 - Cluster 5 - Nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(nrp) + (nrp) + (thr-ser-thr)
METTRDRAFT_RS0211125
NRPSPredictor2 SVM: hydrophilic
Stachelhaus code: ala
Minowa: glu
consensus: nrp

Search NORINE for peptide in strict mode // relaxed mode

METTRDRAFT_RS0211155
NRPSPredictor2 SVM: N/A
Stachelhaus code: N/A
Minowa: qa
consensus: nrp

Search NORINE for peptide in strict mode // relaxed mode

METTRDRAFT_RS0211255
NRPSPredictor2 SVM: thr
Stachelhaus code: thr
Minowa: thr
consensus: thr

NRPSPredictor2 SVM: ser
Stachelhaus code: ser
Minowa: ser
consensus: ser

NRPSPredictor2 SVM: thr
Stachelhaus code: thr
Minowa: thr
consensus: thr

Search NORINE for peptide in strict mode // relaxed mode

Database cross-links

Link to NORINE database query form
Direct lookup in NORINE database in strict mode // relaxed mode

Gene cluster description

Download cluster GenBank file
NZ_ADVE02000001 - Gene Cluster 5. Type = nrps. Location: 2261178 - 2342632 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Homologous known gene clusters

NZ_ADVE02000001 - Cluster 6 - Other

Gene cluster description

Download cluster GenBank file
NZ_ADVE02000001 - Gene Cluster 6. Type = other. Location: 2571865 - 2614669 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

NZ_ADVE02000001 - Cluster 7 - Terpene

Gene cluster description

Download cluster GenBank file
NZ_ADVE02000001 - Gene Cluster 7. Type = terpene. Location: 2709683 - 2755892 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

NZ_ADVE02000001 - Cluster 8 - Other

Gene cluster description

Download cluster GenBank file
NZ_ADVE02000001 - Gene Cluster 8. Type = other. Location: 3414014 - 3456908 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Homologous known gene clusters