Identified secondary metabolite clusters

Cluster Type From To Most similar known cluster MIBiG BGC-ID
The following clusters are from record CP001280.1:
Cluster 1Hserlactone80840101457--
Cluster 2Bacteriocin338064348954--
Cluster 3Nrps921192965319--
Cluster 4Other10640921108168--
Cluster 5Nrps-T1pks12897681362347--
Cluster 6Terpene22339682255035--
Cluster 7T1pks29678643015342Sphingan_polysaccharide_biosynthetic_gene_cluster (17% of genes show similarity)BGC0000797_c1
Cluster 8Terpene31320643152927--
Cluster 9Terpene35443463569613Malleobactin_biosynthetic_gene_cluster (7% of genes show similarity)BGC0000386_c1
Cluster 10Bacteriocin-Nrps36272443668485Vicibactin_biosynthetic_gene_cluster (44% of genes show similarity)BGC0000457_c1
Cluster 11T3pks37009303742012--
Cluster 12Bacteriocin40506704061509--

CP001280 - Cluster 1 - Hserlactone

Gene cluster description

Download cluster GenBank file
CP001280 - Gene Cluster 1. Type = hserlactone. Location: 80840 - 101457 nt. Click on genes for more information.
Show pHMM detection rules used
hserlactone: (Autoind_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

CP001280 - Cluster 2 - Bacteriocin

Gene cluster description

Download cluster GenBank file
CP001280 - Gene Cluster 2. Type = bacteriocin. Location: 338064 - 348954 nt. Click on genes for more information.
Show pHMM detection rules used
bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Bacteriocin_Iii or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03605 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03882 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

CP001280 - Cluster 3 - Nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(ile)
Msil_0855
NRPSPredictor2 SVM: ile
Stachelhaus code: ile
Minowa: val
consensus: ile

Search NORINE for peptide in strict mode // relaxed mode

Database cross-links

Link to NORINE database query form
Direct lookup in NORINE database in strict mode // relaxed mode

Gene cluster description

Download cluster GenBank file
CP001280 - Gene Cluster 3. Type = nrps. Location: 921192 - 965319 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

CP001280 - Cluster 4 - Other

Gene cluster description

Download cluster GenBank file
CP001280 - Gene Cluster 4. Type = other. Location: 1064092 - 1108168 nt. Click on genes for more information.
Show pHMM detection rules used
other: ((PP-binding & AMP-binding) or (PP-binding & A-OX) or (NAD_binding_4 & A-OX) or (NAD_binding_4 & AMP-binding) or LmbU or Neocarzinostat or cycdipepsynth or fom1 or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

CP001280 - Cluster 5 - Nrps-t1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(val) + (mal-gly) + (nrp)
Msil_1226
NRPSPredictor2 SVM: gly,ala,val,leu,ile,abu,iva
Stachelhaus code: lys
Minowa: 4-mha
consensus: nrp

Search NORINE for peptide in strict mode // relaxed mode

Msil_1247
PKS signature: mal
Minowa: mal
consensus: mal

NRPSPredictor2 SVM: gly
Stachelhaus code: gly
Minowa: gly
consensus: gly

Search NORINE for peptide in strict mode // relaxed mode

Msil_1248
NRPSPredictor2 SVM: val
Stachelhaus code: val
Minowa: val
consensus: val

Search NORINE for peptide in strict mode // relaxed mode

Database cross-links

Link to NORINE database query form
Direct lookup in NORINE database in strict mode // relaxed mode

Gene cluster description

Download cluster GenBank file
CP001280 - Gene Cluster 5. Type = nrps-t1pks. Location: 1289768 - 1362347 nt. Click on genes for more information.
Show pHMM detection rules used
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

CP001280 - Cluster 6 - Terpene

Gene cluster description

Download cluster GenBank file
CP001280 - Gene Cluster 6. Type = terpene. Location: 2233968 - 2255035 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

CP001280 - Cluster 7 - T1pks

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(redmal)
Msil_2723
PKS signature: mal
Minowa: mal
consensus: redmal

Gene cluster description

Download cluster GenBank file
CP001280 - Gene Cluster 7. Type = t1pks. Location: 2967864 - 3015342 nt. Click on genes for more information.
Show pHMM detection rules used
t1pks: ((PKS_KS & PKS_AT) or (ene_KS & PKS_AT) or (mod_KS & PKS_AT) or (hyb_KS & PKS_AT) or (itr_KS & PKS_AT) or (tra_KS & PKS_AT))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Homologous subclusters

Homologous known gene clusters

CP001280 - Cluster 8 - Terpene

Gene cluster description

Download cluster GenBank file
CP001280 - Gene Cluster 8. Type = terpene. Location: 3132064 - 3152927 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

CP001280 - Cluster 9 - Terpene

Gene cluster description

Download cluster GenBank file
CP001280 - Gene Cluster 9. Type = terpene. Location: 3544346 - 3569613 nt. Click on genes for more information.
Show pHMM detection rules used
terpene: (Terpene_Synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

Homologous known gene clusters

CP001280 - Cluster 10 - Bacteriocin-nrps

Predicted core structure

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Prediction details

Monomers prediction:
(orn)
Msil_3319
NRPSPredictor2 SVM: glu,gln
Stachelhaus code: orn
Minowa: orn
consensus: orn

Search NORINE for peptide in strict mode // relaxed mode

Database cross-links

Link to NORINE database query form
Direct lookup in NORINE database in strict mode // relaxed mode

Gene cluster description

Download cluster GenBank file
CP001280 - Gene Cluster 10. Type = bacteriocin-nrps. Location: 3627244 - 3668485 nt. Click on genes for more information.
Show pHMM detection rules used
bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Bacteriocin_Iii or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03605 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03882 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692)
nrps: ((Condensation & AMP-binding) or (Condensation & A-OX) or cluster(Condensation,AMP-binding))

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

Homologous gene clusters

Homologous known gene clusters

CP001280 - Cluster 11 - T3pks

Gene cluster description

Download cluster GenBank file
CP001280 - Gene Cluster 11. Type = t3pks. Location: 3700930 - 3742012 nt. Click on genes for more information.
Show pHMM detection rules used
t3pks: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters

CP001280 - Cluster 12 - Bacteriocin

Gene cluster description

Download cluster GenBank file
CP001280 - Gene Cluster 12. Type = bacteriocin. Location: 4050670 - 4061509 nt. Click on genes for more information.
Show pHMM detection rules used
bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Bacteriocin_Iii or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03605 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03882 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692)

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous gene clusters