LOCUS       CP001280               20864 bp    DNA              UNK 01-JAN-1980
DEFINITION  Methylocella silvestris BL2, complete genome.
ACCESSION   CP001280
VERSION     CP001280.1
KEYWORDS    .
SOURCE      .
  ORGANISM  .
            .
FEATURES             Location/Qualifiers
     cluster         1..20864
                     /note="Cluster number: 8"
                     /note="Detection rule(s) for this cluster type: terpene:
                     (Terpene_Synth or Terpene_synth_C or phytoene_synt or
                     Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or
                     fung_ggpps2 or trichodiene_synth);"
                     /clusterblast="2. CP001016_c4	Beijerinckia indica subsp.
                     indica ATCC 9039, complete genome. (38% of genes show
                     similarity)"
                     /clusterblast="3. NZ_ARWA01000001_c3	Methyloferula stellata
                     AR4 strain AR4T A3OQDRAFT_chromo... (38% of genes show
                     similarity)"
                     /clusterblast="4. NZ_ALIQ01000116_c1	Chelatococcus sp. GW1
                     contig000116, whole genome shotgu... (19% of genes show
                     similarity)"
                     /clusterblast="5. CP001349_c5	Methylobacterium nodulans ORS
                     2060, complete genome. (19% of genes show similarity)"
                     /clusterblast="6. JH660645_c2	Microvirga sp. WSM3557
                     genomic scaffold Micloscaffold_13, whol... (19% of genes
                     show similarity)"
                     /clusterblast="7. JPUG01000064_c1	Microvirga sp. BSC39
                     scf7180000028486, whole genome shotgu... (19% of genes show
                     similarity)"
                     /clusterblast="8. JPKG01000013_c1	Bosea sp. LC85 contig20,
                     whole genome shotgun sequence. (19% of genes show
                     similarity)"
                     /clusterblast="9. CP000943_c6	Methylobacterium sp. 4-46,
                     complete genome. (19% of genes show similarity)"
                     /clusterblast="10. NZ_AQVT01000001_c3	Methylobacterium sp.
                     88A A3OMDRAFT_contig1.1_C, whole ... (19% of genes show
                     similarity)"
                     /clusterblast="11. CP001029_c6	Methylobacterium populi
                     BJ001, complete genome. (19% of genes show similarity)"
                     /product="terpene"
     sig_peptide     1721..1837
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.965) with cleavage site probability 0.425 at
                     residue 39"
                     /locus_tag="Msil_2849"
     gene            1721..2986
                     /locus_tag="Msil_2849"
     CDS             1721..2986
                     /locus_tag="Msil_2849"
                     /codon_start=1
                     /product="efflux transporter, RND family, MFP subunit"
                     /transl_table=11
                     /note="TIGRFAM: efflux transporter, RND family, MFP
                     subunit; PFAM: secretion protein HlyD family protein; KEGG:
                     bac:BamMC406_1967 efflux transporter, RND family, MFP
                     subunit"
                     /note="smCOG:
                     SMCOG1029:RND_family_efflux_transporter_MFP_subunit (Score:
                     197.4; E-value: 2.881e-59);"
                     /note="smCOG tree PNG image: smcogs/Msil_2849.png"
                     /db_xref="GI:217504358"
                     /db_xref="InterPro:IPR006143"
                     /translation="MSMKSDAPAEKPRRFRLIFCTALLAVLGLAASGLVERAKSKQELA
                     AWTEDQAIPTVRTVQPQRGPSEEQLSLPGNVKAYYTGSLYARASGYVTAWRKDIGARVK
                     KGEVLAEIAAPDLDQQLVQAKAQLVQLKAQVEQARANADLGQLTDQRTSRLVAKGWSSA
                     QQGDTDRLTAASRLAALDVAKANVEAQQAAVGRLEELTRFKQIVAPFDGVVTARNVDVG
                     DLVNADGKSGKALFQVSDIHEMRIYVNVPQAFLGQMTPGLRASLDLPGQEQSFEATLVS
                     TSNALSEDSRTSLAQLQAANPEGKLWPGAFAEVHFHIPSDQNTLHVPATALIFGSDGMN
                     VAAVGADGRVELKKVGLGRNLGASVEIRSGVSLSDKIIDNPLEMIASGDVVRLAGADAA
                     VATAREARAEARATAARSERMN"
                     /protein_id="ACK51767.1"
     gene            complement(3053..3333)
                     /locus_tag="Msil_2850"
                     /pseudo
     gene            3438..4445
                     /locus_tag="Msil_2851"
     CDS             3438..4445
                     /locus_tag="Msil_2851"
                     /codon_start=1
                     /product="TIM-barrel protein, yjbN family"
                     /transl_table=11
                     /note="TIGRFAM: TIM-barrel protein, yjbN family; PFAM:
                     dihydrouridine synthase DuS; KEGG: bid:Bind_0998 TIM-barrel
                     protein, YjbN family"
                     /db_xref="GI:217504359"
                     /db_xref="InterPro:IPR001269"
                     /db_xref="InterPro:IPR004653"
                     /translation="MKQYQAYRFSVAPMMDWTDRHCRSFHRLLTRRARLYTEMVTTGAV
                     LHGQRDRLLGFDAAEHPLAAQLGGSDPADLAAAARICADFGYDEINLNAGCPSKRVQNG
                     AFGACLMREPELVGDCVAAMKAAVSAPVTVKCRIGVDEQEPREALFAFAETVLGAGADA
                     LIVHARKAWLEGLSPKDNRHIPPLDYALVHELKRRFPDTPIAINGGLDTIDAMRAQLDH
                     VDGVMIGRAAYQDPALLLEVDPVFFGEDAPFSEMAQAIEAFTPYIAARLTEGVPLNAMV
                     RHLLGAFNGRPGARAFRRHLATESVKPGAGLEVLRAALALIGSRAGEDQAEAAE"
                     /protein_id="ACK51768.1"
     gene            complement(4512..5411)
                     /locus_tag="Msil_2852"
     CDS             complement(4512..5411)
                     /locus_tag="Msil_2852"
                     /codon_start=1
                     /product="protein of unknown function DUF815"
                     /transl_table=11
                     /note="PFAM: protein of unknown function DUF815; KEGG:
                     bid:Bind_0999 protein of unknown function DUF815"
                     /db_xref="GI:217504360"
                     /db_xref="InterPro:IPR008533"
                     /translation="MTSSEPYDAPSLSRAAEALERIAAALERLVPAAPERQDFSAADAF
                     IFSAHAPHLSAVARVNRVDMALLRGIDRLRDILTDNTERFARGFPANNALLWGARGMGK
                     SSLVKAAHADVNTRLSGVGGLAPLKLIEIHREDIDSLPLLMGVLREASYRFVVFCDDLS
                     FDAADTNYKSLKAVLEGGIEGRPQNVLFYATSNRRHILSREMVDNERGTAINPGEAVEE
                     KVSLSDRFGLWLGFHACSQAEYLDMVFGYAEHFGLAQDRPAIEREALEWAITRGARSGR
                     TAFQYIQDLAGRLGKRLD"
                     /protein_id="ACK51769.1"
     sig_peptide     5572..5664
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.998) with cleavage site probability 0.882 at
                     residue 31"
                     /locus_tag="Msil_2853"
     gene            5572..6342
                     /locus_tag="Msil_2853"
     CDS             5572..6342
                     /locus_tag="Msil_2853"
                     /codon_start=1
                     /product="Carbonate dehydratase"
                     /EC_number="4.2.1.1"
                     /note="PFAM: carbonic anhydrase; KEGG: rpb:RPB_4625
                     carbonate dehydratase"
                     /db_xref="GI:217504361"
                     /db_xref="InterPro:IPR001148"
                     /db_xref="InterPro:IPR006311"
                     /translation="MTKSSLGRREALKALAAFGFCAACAKASLAGEAAAHWSYEGDHGP
                     AHWGDLDAADKICAIGSQQSPIAIDSSIAAELPPLRFDWPVDAAEIVNNGHTIQLNFDE
                     GAALKVGPDVWRLAQLHFHHPCEHLIDDKASAMEIHFVHRNEKGLAVVGALVKPGKSNP
                     TFRKIVAAMPGAEGPAQKAPAGLNPRGLLPKARGYFRYSGSLTTPPCSETVDWLVLRHP
                     VEVLSADIDAFAELYPMNARPAQQIDRRFVLRSV"
                     /transl_table=11
                     /protein_id="ACK51770.1"
     gene            6549..6893
                     /locus_tag="Msil_2854"
     CDS             6549..6893
                     /locus_tag="Msil_2854"
                     /codon_start=1
                     /product="preprotein translocase, YajC subunit"
                     /transl_table=11
                     /note="TIGRFAM: preprotein translocase, YajC subunit; PFAM:
                     YajC family protein; KEGG: bid:Bind_1000 preprotein
                     translocase, YajC subunit"
                     /db_xref="GI:217504362"
                     /db_xref="InterPro:IPR003849"
                     /translation="MFTPAFAQAAGGAGGGATDLIVQLIPFALILAIMYFLIMRPQQKR
                     AREHADLIKNLRRGDSVVTSGGLIGKVTKVIDDAEVELEIAPNVRVRVARGLVTDVRSK
                     GEPVKDAANS"
                     /protein_id="ACK51771.1"
     sig_peptide     6956..7060
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.995) with cleavage site probability 0.802 at
                     residue 35"
                     /locus_tag="Msil_2855"
     gene            6956..8554
                     /locus_tag="Msil_2855"
     CDS             6956..8554
                     /locus_tag="Msil_2855"
                     /codon_start=1
                     /product="protein-export membrane protein SecD"
                     /transl_table=11
                     /note="TIGRFAM: protein-export membrane protein, SecD/SecF
                     family; protein-export membrane protein SecD; PFAM:
                     SecD/SecF/SecDF export membrane protein; KEGG:
                     bid:Bind_1001 protein-export membrane protein SecD"
                     /note="smCOG:
                     SMCOG1035:MMPL_domain-containing_transport_protein (Score:
                     22.6; E-value: 1.225e-06);"
                     /note="smCOG tree PNG image: smcogs/Msil_2855.png"
                     /db_xref="GI:217504363"
                     /db_xref="InterPro:IPR003335"
                     /db_xref="InterPro:IPR005791"
                     /translation="MLRFATWKIVSIVMMTVIALLLIVPSLLGPQSRAALMAHAPSFLP
                     IRPIVLGLDLQGGSHVLLEVDGQSVVKTLIDNLRDSVRRTLREEKASISGGIGVLPRGV
                     QLRIPDAAERERIMPKLRLLTAPASAGISGVGGASVFDVTETADGLIQFTVTEAGIKAK
                     MRRAVEQSIEVLRRRVDALGTTEPNIQRQGDDRVLVEVPGLQDTGKLKEILGTTAKLEF
                     RLVSDTGADPAETEMLEEVERPGSKLPVQKRVMVQGEDLTDAQPGFDQRTQEPVVNFRF
                     NIRGGQRFGEVTSENVGRPFAIVLDGKVISAPRILGPITGGSGQISGHFTVESANNLAI
                     LLRAGALPAKLTIVEERTVGPGLGQDSIDAGKRAAYVGAALVACYMLITYGIFGVFANI
                     ALFVHIAFIFAGLVLLGATLTLPGIAGIVLTIGMAVDSNVLIYERIREESHAGRSIVSS
                     LDAGFKRAFATIVDSNVTMFVAAAILYFLGSGPVRGFAVSLALGILTTIVTAVTMTRMM
                     ITLWYRYKRPVKLPI"
                     /protein_id="ACK51772.1"
     gene            8590..9546
                     /locus_tag="Msil_2856"
     CDS             8590..9546
                     /locus_tag="Msil_2856"
                     /codon_start=1
                     /product="protein-export membrane protein SecF"
                     /transl_table=11
                     /note="TIGRFAM: protein-export membrane protein, SecD/SecF
                     family; protein-export membrane protein SecF; PFAM:
                     SecD/SecF/SecDF export membrane protein; KEGG:
                     bid:Bind_1002 protein-export membrane protein SecF"
                     /db_xref="GI:217504364"
                     /db_xref="InterPro:IPR003335"
                     /db_xref="InterPro:IPR005665"
                     /translation="MKLLRLAPENTKFPFMRFRRISYPFSAVMSIISVVLFLTLGMNFG
                     IDFSGGTLVELRAKSGAADIAQLRAIAENMHVGEVEVQGFGQPSDVTLRFGVQHSEQGD
                     AAAQEAAIARVKDAVGNDYEFRRVEVVGPRVSGELVQSGTLGVVVAIVAVLCYLWFRFE
                     WQFAVGAIIATMHDLLLTVGFFSLTRLEFNTTSIAAILTIVGYSLNETVVVLDRIREMM
                     RKYRKMPTDELIDLSVNAVLPRTIMTATTVFLALLSLVVFGGQVIRSFSIAMIWGIFVA
                     TYSSVFICSPMLIYLGLRNETVGPEPTPGGKLAKNPA"
                     /protein_id="ACK51773.1"
     gene            9603..10001
                     /locus_tag="Msil_2857"
     CDS             9603..10001
                     /locus_tag="Msil_2857"
                     /codon_start=1
                     /product="protein of unknown function DUF498"
                     /transl_table=11
                     /note="PFAM: protein of unknown function DUF498; KEGG:
                     bid:Bind_1003 protein of unknown function DUF498"
                     /db_xref="GI:217504365"
                     /db_xref="InterPro:IPR007523"
                     /translation="MPTDAHEPKCPGFLPGAHAIDGYGSGGFRFGGMSHRGSILALPSG
                     VYAWSALEPADITAASLGQLFAEERGLIEHVLIGVGVAMGSLDAELKRRLNAAGIRAEP
                     MQTGAAARTYNILLGEKRRVAAALLAVP"
                     /protein_id="ACK51774.1"
     gene            10001..10864
                     /locus_tag="Msil_2858"
     CDS             10001..10864
                     /locus_tag="Msil_2858"
                     /codon_start=1
                     /product="Squalene/phytoene synthase"
                     /transl_table=11
                     /note="PFAM: Squalene/phytoene synthase; KEGG:
                     bid:Bind_1004 squalene/phytoene synthase"
                     /db_xref="GI:217504366"
                     /db_xref="InterPro:IPR002060"
                     /sec_met="Type: terpene"
                     /sec_met="Domains detected: phytoene_synt (E-value:
                     3.4e-23, bitscore: 80.0, seeds: 8)"
                     /sec_met="Kind: biosynthetic"
                     /translation="MSEALSALDADYAYCETIVRRDDPDRWLASLFLPEGKRRYAHALY
                     AFSLEIARVREVVSEPMLGEIRFQWWREALEQPDREDVRANPVAAAVTDVLVRFDLPSE
                     HLLQLIDARQFDLFDDPMQSVDELEAYARATSSNLFCLTPMILEPETPSSGFGAASHGG
                     TAYALTGLLRAFPWHAARGQCYVPLDILRRHGLERADAVSGRASPALLAALEEFRALAR
                     SHLEIFLTRIEGLPDLARPAFLPICLCEPYLRLMEGKCYDPFKTNVVLPQWRRQWALWR
                     AAKHWQ"
                     /protein_id="ACK51775.1"
     gene            10993..11253
                     /locus_tag="Msil_2859"
     CDS             10993..11253
                     /locus_tag="Msil_2859"
                     /codon_start=1
                     /product="hypothetical protein"
                     /transl_table=11
                     /db_xref="GI:217504367"
                     /translation="MRIQSEGQPHAGEDFHFSVSGGAGAKTLKAYIEYKTVLDISFSGD
                     LQQTLAIPSQTGKFTLKLLAHDGAGESAEMRYVIAGEPPAP"
                     /protein_id="ACK51776.1"
     gene            11481..14696
                     /locus_tag="Msil_2860"
     CDS             11481..14696
                     /locus_tag="Msil_2860"
                     /codon_start=1
                     /product="isoleucyl-tRNA synthetase"
                     /transl_table=11
                     /note="TIGRFAM: isoleucyl-tRNA synthetase; KEGG:
                     bid:Bind_1006 isoleucyl-tRNA synthetase"
                     /db_xref="GI:217504368"
                     /db_xref="InterPro:IPR001412"
                     /db_xref="InterPro:IPR002300"
                     /db_xref="InterPro:IPR002301"
                     /db_xref="InterPro:IPR010663"
                     /db_xref="InterPro:IPR013155"
                     /db_xref="InterPro:IPR015413"
                     /db_xref="InterPro:IPR015905"
                     /translation="MNEIETARGVLRTAEGKGGGEAKSGPDYSKSLYLPQTDFPMRAGL
                     PKKEPELLARWREIGLYERMREAARGRPKFVLHDGPPYANGDIHIGHALNKILKDLIAR
                     SQQMLGADANYVPGWDCHGLPIEWKIEEQYRAKGRSKDEVPVNEFRRECRAFAEHWVEI
                     QREQFKRLGVNGDWDHPYLTMTYPAEATIAREIMKFAENGLLYRGSKPVMWSVVEKTAL
                     AEAEVEYEDHVSDWVFVAFPVKRVGAVGLPEDIVPGVVSAHPNNDALEKASIVIWTTTP
                     WTVPANRAISFSAKIPYGLYRMTLAPEGNWAPIGATYLLADALADGVFKSAKVESYEKV
                     CDVPPDYLRALTAAHPFAATIPGYEFAVPLFDGDHVTADTGTGFVHTAPGHGRDDYDIW
                     TSHKRFLEERGIDTRIPFTVDADGFLTREAPGFARHRVIDDKGNKGDANEAVIKALIEA
                     GNLLARGRLKHQYPHSWRSKKPLIFRNTPQWFIALDKDFELPQYPLTSPQNPLTLRSGQ
                     SPRLEGRGDGASLATRAPSSFETPPTTASPQDEGFAPTLRAIALAEIAKTKWVPAAGEN
                     RITGMIANRPDWVVSRQRAWGVPIAIFVNKESGDILKDRQVNARITEAFAAEGADAWFA
                     EGAKARFLGNAHNPEAFEKIDDVLDVWFDSGSTHAFTLDDPQNFPGLAGIRRKRDGGDD
                     EIMYLEGSDQHRGWFHSSLLESCGTRGRAPFDLVLTHGFVLDEKGQKMSKSQGNVTAPQ
                     TIIKDAGADILRLWVAASDYSDDLRIGPEILKTFIETYRKLRNTIRWMLGTLAHYEPER
                     AVAVEQMEELERLMLHRLKELDEDIRDAYQRFDLKRVVARLSSFLNSDLSAFYFDIRKD
                     ALYCEPPSSLKRLAALTAIEQIFRAVTLWLAPILVFTSEEAWLSRYREKISIHLETLPD
                     LPDEWRDEALVVKWGKIRRIRSVVTAALEIERAQKRIGSSLEAAPQVFIADPDLKSALE
                     GVDFAEICIASDISIADGEGPIDAFRLDEVPGVAVVPRRAEGRKCARSWRISPLVGSDP
                     DYPDVTPRDARALRELQAAGLWP"
                     /protein_id="ACK51777.1"
     sig_peptide     14693..14743
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.993) with cleavage site probability 0.440 at
                     residue 17"
                     /locus_tag="Msil_2861"
     gene            14693..15208
                     /locus_tag="Msil_2861"
     CDS             14693..15208
                     /locus_tag="Msil_2861"
                     /codon_start=1
                     /product="lipoprotein signal peptidase"
                     /transl_table=11
                     /note="TIGRFAM: lipoprotein signal peptidase; PFAM:
                     peptidase A8 signal peptidase II; KEGG: bid:Bind_1007
                     lipoprotein signal peptidase"
                     /db_xref="GI:217504369"
                     /db_xref="InterPro:IPR001872"
                     /translation="MSPRVLGALVAALTLAADQANKLWLIFVYGIEQRQPIALAPFLDV
                     VYAKNPGISYSLLSARTDFQRYALLGLTLAATIFMILWLWRSTSKLIACALGLIIGGAL
                     GNAYDRAAYGFVADFYHFHVGSFSWYVFNLADAAIVAGVALLLYDSLFSARGAGTGGKS
                     RGEGASAL"
                     /protein_id="ACK51778.1"
     sig_peptide     15299..15403
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.998 at
                     residue 35"
                     /locus_tag="Msil_2862"
     gene            15299..16000
                     /locus_tag="Msil_2862"
     CDS             15299..16000
                     /locus_tag="Msil_2862"
                     /codon_start=1
                     /product="conserved hypothetical protein"
                     /transl_table=11
                     /note="KEGG: bid:Bind_1008 hypothetical protein"
                     /db_xref="GI:217504370"
                     /translation="MASNRMSADRVRLLRLLAVSLAFSGLAGFSPARAQAPQEDTNPLN
                     SVLGFIGMQFDKDRESIDYRARAPIVVPPRTDLPKPKVASRDASWPSDPDIGERRHAAA
                     EAQRPAPQLTPQARVELSPAELAGGVGGHATDAPRAAEDDCQPGAGTPICLYTPWKALQ
                     SMVGLGGGSSPDKVDPGVEPDRRYLTEPPIGYRKATAAAAATIDAPKDQPDSSDAQAYN
                     RSQRHKSSVDE"
                     /protein_id="ACK51779.1"
     gene            16288..17661
                     /locus_tag="Msil_2863"
     CDS             16288..17661
                     /locus_tag="Msil_2863"
                     /codon_start=1
                     /product="peptidase M16 domain protein"
                     /transl_table=11
                     /note="PFAM: peptidase M16 domain protein; KEGG:
                     bid:Bind_1009 peptidase M16 domain protein"
                     /db_xref="GI:217504371"
                     /db_xref="InterPro:IPR001431"
                     /db_xref="InterPro:IPR007863"
                     /db_xref="InterPro:IPR011765"
                     /translation="MSFAPPQASSLTPSAEAPAKPSGPVIGQAKLANGLEIVVIPDHRS
                     PVVTHMVWYRNGSADDPLGKSGIAHFLEHLMFKGTSTHPQGEFSQLVADSGGQENAFTS
                     NDYTAYFQRVARDQLAVCMEYEADRMKNLVLTDEIVAPEREVVLEERRMRTDSDPSDQL
                     NEAVQAALFTQHPYGRPIIGWNHEIESLDRSDALAYYDRFYTPENAILVVAGDVSTEEV
                     VELAEKIYGPIPARGEPPKRERPREPEQRAHRLVTLADEKVEQPAHHGVYLVPSYHTAA
                     PGVAEALEVLGHLLGAGHTSLLFKNLVIDQKIAVGAGAHYLGSAVDDTRFYVYAVPAEG
                     VSLERLDAAIDEIIARVAAEGVDEADFKRAKTRLIADAVYAQDNQASLARWYGASLATG
                     LSIEDVTQWPQRIDAVAREDVRQAARLLDKKRSVTGFLLSAPAGDEAPRDGLEAALTA"
                     /protein_id="ACK51780.1"
     gene            17717..19024
                     /locus_tag="Msil_2864"
     CDS             17717..19024
                     /locus_tag="Msil_2864"
                     /codon_start=1
                     /product="peptidase M16 domain protein"
                     /transl_table=11
                     /note="PFAM: peptidase M16 domain protein; KEGG:
                     bid:Bind_1010 peptidase M16 domain protein"
                     /db_xref="GI:217504372"
                     /db_xref="InterPro:IPR007863"
                     /db_xref="InterPro:IPR011765"
                     /translation="MTPTAALETPAPLKPAESRSRAAQVQKIVSSGGVEAWLVEDYAVP
                     LVAVEFAFKGGASQDPAGKPGTANLLSGLLDEGAGPYDAEGFHRALDEDAIELSFSADR
                     DNFHGRLQTLSRNVAPAFSLMRLAVNEARLDDEPFKRVSSQIAASLKREVNDPDHVASR
                     AFREKAYLGHPYGRPVRGDLDVLPTLTRDDLVDLRTAVFARETLKIAVVGAIDAEALKR
                     HLDDVFGALPQAAGLIATPEAEFSSLGQRFVVDVDVPQSTIRFGRPGLAQRDPDFFAGM
                     VVNHVLGGGVFSARLFREVREKRGLAYSVYSQLLNYDHGAMLYGGTSTKNERAAESMAV
                     IEAEIRNLSEVGPTEEELDKAKKYLIGSYALRFDTSTKIASQLLHLQTDGFDVDQLDER
                     NRRIAAATMEDAKRAAKRLFGDASLLVAVAGRPVGM"
                     /protein_id="ACK51781.1"
     gene            19073..19576
                     /locus_tag="Msil_2865"
     CDS             19073..19576
                     /locus_tag="Msil_2865"
                     /codon_start=1
                     /product="conserved hypothetical protein"
                     /transl_table=11
                     /note="KEGG: smd:Smed_5447 hypothetical protein"
                     /db_xref="GI:217504373"
                     /translation="MARKKIAFESPFPTPAFEPESRAALRKAMEEARRCGRDDLWREAL
                     RKLCALDGIDLSDPLHCSFYETLGAYEQALTEKNGRTTRASRTRQKIRNKGIVGCLEDW
                     ALAPAPTEGFEMLIRTGRAELTGEFLLLRYPDRFSDKAVAAARARLERAGIDPPSPAPT
                     RPRD"
                     /protein_id="ACK51782.1"
     gene            complement(19596..20183)
                     /locus_tag="Msil_2866"
     CDS             complement(19596..20183)
                     /locus_tag="Msil_2866"
                     /codon_start=1
                     /product="GCN5-related N-acetyltransferase"
                     /transl_table=11
                     /note="PFAM: GCN5-related N-acetyltransferase; KEGG:
                     hne:HNE_1683 acetyltransferase"
                     /note="smCOG: SMCOG1111:GCN5-related_N-acetyltransferase
                     (Score: 31.2; E-value: 3.3e-09);"
                     /note="smCOG tree PNG image: smcogs/Msil_2866.png"
                     /db_xref="GI:217504374"
                     /db_xref="InterPro:IPR000182"
                     /translation="MERSTFAPGQPPGCGLIIRDADEKDMAPALAIYAHHVLHGLATFE
                     ETPPTIGEFAARRAAALEQGLPFLIAALDGTIVGYSYAAEYRARTAYRHTIEDSVYVAV
                     GLGGRGVGTMLLAALIERCEAGPWRQMIAVIGDSGNAGSIALHKNLGFAHRGTLRSVGR
                     KLGQWIDTVLMQRPLGAGDASIPGEGEGAKQM"
                     /protein_id="ACK51783.1"
ORIGIN
        1 ccttctgcgc aatcatcggc ctcagccgca tggcgcaggc gcgcccgaga gcgccaatcc
       61 cttcgttcgc ctccagcgcg cgtttgagcg tcgcttcgag cagctgcgca aattctatgt
      121 ggcctccttg caactcgcgc tcgcgaaccg tctgcgcttt gcgggaggga ctctttcgtt
      181 cgccgtgttg tcgctcgctc tcttccctgc gctcggacag gatttctttc cagcggtgga
      241 agggggcgcg atcaagattc acattcgcgc gccgaacggc gtccgcgtcg aaggaacgac
      301 tgtcctttgt caacagatcg acgcagccgt ccgcgacatc attccgccgg atcgcatcga
      361 gagcatcgtc gacaatatcg gcctgcccaa tagcggcatc aatttgacct atggcaattc
      421 cgggacgatc ggcgtgagcg acgccgacat tctcattacg ctcaaggaag ggcgggtttc
      481 cagcgcggac tatgaaaaga tcctgcgcga gaaattgccg agggcgtttc ccggcgtgac
      541 cttcgcgttt ctgccggcgg atatcgtcag ccagattctg aatttcggat cgccgtcgcc
      601 gctcgatgtg cagatcgccg gtcagaacat caacgccaat cgcgaattcg cccgcctgtt
      661 gcttacgcgg atgcgccgcg tccccggcat tgcggacgcg cgcgttcacg aggtctttca
      721 ggcgccggcg ctcaaggtcg aattcaatcg cgagctcgcg ggccttgtcg ggcttaccga
      781 gcgcgacgct tcgacaaatc tccagagcac gctgtccggg agcgcccagg tcgcgccgac
      841 ttattggctc aatcccgcga acggcgtgtc ttaccccgtt tcgatccaga cgccgcaata
      901 tgacatcgac actctggccg gcctcaagaa tttaccgttg tcgaacgagc aatcgacgca
      961 gctgctcggg gccgtcgcca acatcacgac ggagcccgcc tccgcgatcg tatcccacta
     1021 caacatccag ccggcgatca acatctatgc ggcgacccag ggacgcgacc tcggcggcgt
     1081 cgccgcggac atcgaaaaga tcatcgcgga catgcgcggc gagctgccga agggatcgag
     1141 cgtcgtcatc cgcggccagg ccgcgaccat gacgagcgcc tatgagcagc tctttttcgg
     1201 gctcggcttc tccatcgtcc tgatctacct tctgatcgtc gtcaattttc agtcgtggct
     1261 cgaccccttc gtgatcatct ccgccctgcc ggctgcgctc gccggcatcg tctggatgct
     1321 ctttctcacc tatacgcccg tctctgtgcc agccctgact ggcgcgatca tgtgcatggg
     1381 cgtcgcgaca gccaacagca ttctcgtcgt cagcttcgcg cgcgagcaat tcgcagccgg
     1441 caaggacgcc gtgacggccg ccatggccgc gggcgcaacc cgtttccggc cggtcatcat
     1501 gaccgcgctc gccatgatca tcggcatgct gcctatggcg atcgaacccg gccagaacgc
     1561 gccgcttgga cgcgccgtta tcggcgggct cttgttcgcg acatgcgcga cccttctctt
     1621 cgtgccggcg gtctttgcaa tcgtccatgg acataaagca agatcggcgt cgaccgagcc
     1681 tctttccgga gagcccttcc atgcatgagg ccgagcgata atgtccatga aatccgacgc
     1741 cccggccgag aagccgcgcc gcttccgatt gatcttctgc acggctctgc tcgccgtcct
     1801 tgggctcgcc gcatcgggcc tcgtggagag ggcgaagagc aaacaggagc ttgccgcctg
     1861 gaccgaagat caggcgattc cgacggtgcg gaccgtgcag ccgcagcgcg gtccgagcga
     1921 ggagcagctg tcgcttccgg gcaatgtgaa agcctattat accggctcgc tctacgcgcg
     1981 ggcgagcggc tacgtcaccg cctggcgcaa ggacatcggc gcgcgggtga aaaaaggcga
     2041 agtgctcgcg gagatcgcgg cgcccgatct cgatcaacag cttgttcagg cgaaagccca
     2101 gctcgttcaa ttgaaggctc aagtcgaaca ggcgcgggcg aacgccgatc tcggccagct
     2161 taccgatcaa aggacgtcgc ggcttgtcgc caagggctgg tccagcgcgc agcagggcga
     2221 taccgaccgg ctgaccgcag cctcgcgcct tgcggcgctc gacgtcgcga aagcgaatgt
     2281 cgaggcgcag caggccgccg tcggccgtct tgaggagctg acgcgattca agcagatcgt
     2341 tgcgcccttc gatggcgtcg tgacagctcg caacgtggac gtcggcgatc tcgtcaacgc
     2401 cgacggcaaa tcgggcaagg ccctgtttca ggtctccgac atccacgaaa tgcgcatcta
     2461 tgtgaacgtc ccgcaggcgt ttcttggcca gatgacgccg ggcctccggg cgtcgctcga
     2521 tctccccggc caggaacagt cgttcgaggc cactttggtc tcgacgtcga acgccctcag
     2581 cgaagactcg cgcacgtctt tggcgcagct tcaggcggcc aatcccgagg gcaaattatg
     2641 gccgggcgcc tttgcggagg tccatttcca cattccctcg gaccagaaca cgctgcacgt
     2701 gccagccacc gcgctgattt ttgggtcgga tggaatgaat gtcgccgccg tcggcgccga
     2761 cggtcgcgtc gaactgaaaa aggtgggtct tgggcgcaat ctcggcgcca gcgtcgagat
     2821 ccgctcggga gtgtcgctgt cggacaagat catcgacaat ccgctggaga tgatcgcgtc
     2881 cggcgatgtc gtccggctcg ccggcgcgga cgccgccgtc gcgaccgctc gcgaggcgcg
     2941 ggccgaggcg cgggcaacgg cggcgcgcag cgagcgcatg aactgaggtc ttagccgaag
     3001 gggggcgacg aaaagaccgg acgctagacc ggcgaggaaa ccttgcattt gccaagtttc
     3061 cgttccgcaa atcgagcgtt gcggccttgg acctgagggg cgtcttgccc accgccgcca
     3121 tatcctccat atggaggccg atcagttccc gaaggttttg atcctgacga cgcgggagct
     3181 tgagggcggc tcgccgcggt cgctttggac ctccccctcc agggcccagc gccgggcgtc
     3241 ctcacgccgc agaaacgtgt cgcttgcata gcgtcccttg cgacgaattt ggactcgccg
     3301 ggaaccggaa ggtagtttgg tgacggcagc cattttcgtg tgcgatcccg tgggcgctcc
     3361 ggcgtcgaaa cgggtcgatt tgcggcgtaa tggagagtgc gcacggcgcg gcctaacgat
     3421 ctgatagtac tgaaaaaatg aagcaatatc aagcatatag attttccgtg gcgcctatga
     3481 tggactggac ggaccggcat tgccggtctt tccatcgtct tctgacccgt cgtgcgcggc
     3541 tgtatacgga aatggtgacg acgggcgcgg tcctgcacgg ccagcgcgac cggctgcttg
     3601 ggttcgacgc ggcggagcat cccctcgctg cgcagcttgg cgggtcggat cccgccgatc
     3661 ttgcggccgc cgcgcgcatc tgcgccgatt tcggctatga cgaaataaac ctcaatgcgg
     3721 gctgcccgtc gaagcgcgtg cagaacggcg ccttcggggc ctgcctcatg cgcgagccgg
     3781 agctcgttgg cgactgcgtc gccgcgatga aggcggccgt gtccgcgccc gtcacggtca
     3841 aatgccgcat cggcgtcgac gagcaggagc cgcgcgaggc gctgttcgcc ttcgcggaaa
     3901 cggtgctcgg agccggcgcc gacgccctga tcgtccatgc gcgcaaagcc tggctggaag
     3961 gcctctcgcc gaaagacaac cgtcatatcc cgccgctcga ttatgcgctg gtccatgagc
     4021 tgaagcggcg tttccccgat acgccgatcg ccatcaatgg cgggctcgat acgatcgacg
     4081 ccatgcgcgc ccaactggat catgtcgacg gcgtgatgat cgggcgcgcc gcctatcagg
     4141 atcccgcgct gctgcttgag gtcgatccgg tcttcttcgg cgaggacgcc cccttctcag
     4201 agatggcgca ggcgatcgag gcttttacgc cctatatcgc ggcgcggctg acggaaggag
     4261 ttccgctcaa cgccatggtc cggcatctgc tcggcgcttt taatggccgg ccgggggcgc
     4321 gcgccttccg ccggcatctg gcgacggaat ccgtcaagcc cggcgccggg cttgaggtcc
     4381 tgcgcgcggc gctggcgctg attggctcga gagcgggcga ggatcaggca gaggcggcgg
     4441 aatagctgcg gccacttcat acgttcggcg tgacgaaggc gccgatcggc ggttctccgc
     4501 cgcaaacggt ctcaatcgag ccgcttgccg agccgccccg cgagatcctg aatatattgg
     4561 aaggcggtgc gccccgagcg agcgccgcgg gtgatcgccc attccagcgc ctcgcgctcg
     4621 atcgcggggc ggtcctgcgc gaggccaaaa tgttcggcgt aaccgaacac catgtcgaga
     4681 tattcggcct gtgaacaggc gtggaagcca agccagagac cgaagcgatc ggacaacgag
     4741 actttctcct cgacggcttc gcccggattg atcgccgtgc cgcgctcatt gtcgaccatc
     4801 tcgcgcgaga ggatatggcg ccggttggag gtcgcgtaga acaggacgtt ttgcgggcgc
     4861 ccctcgatgc cgccctcgag caccgccttc agcgatttat aattcgtgtc ggcggcgtcg
     4921 aaggaaagat cgtcgcaaaa cacgacgaag cgataggacg cctcgcgcaa cacccccatc
     4981 agcagcggca ggctgtcgat gtcttcgcga tggatctcaa tcagtttcag gggcgcgagc
     5041 ccgccgacgc cgctgaggcg cgtgttgacg tcggcgtgcg ccgccttgac cagcgaggat
     5101 ttgcccattc cgcgcgcgcc ccacaaaagc gcgttattgg ccggaaatcc gcgcgcgaag
     5161 cgctcggtat tgtcggtcaa tatgtcgcgc agccggtcga tgccgcgcag cagcgccatg
     5221 tcgacgcgat tgacccgtgc gacggcggac agatgcggcg catgggccga gaagataaag
     5281 gcgtcggcgg cggagaaatc ctgtctttca ggcgccgcgg ggaccagccg ctccagcgcc
     5341 gccgcgatcc gctcgagggc ctcggcagcg cgggacaggg acggggcgtc atagggttcg
     5401 gaactggtca tttgcgcgga tcggcccgat cgggaaaggc gcgttttaga gcatgatcga
     5461 aggcgcttgg ccagatggcg atctggccgc tgattgacgg tcgcggcgat ttggctaatc
     5521 ctcgcaacct taaccgtcgc caatgaacga cggggtcgat cgggggtcga aatgacgaag
     5581 tcgagcctgg ggcgccgcga agcgctaaaa gccttggccg cgtttggctt ttgcgctgct
     5641 tgcgccaagg cgagcctggc gggagaagcg gcggcgcatt ggagctatga aggggatcac
     5701 ggcccggcgc attggggcga tctcgacgcc gccgacaaga tctgcgcgat cggcagtcag
     5761 caatcgccga tcgccatcga cagctccatc gcggcggagc tgcctccgct ccgcttcgac
     5821 tggcccgtcg acgccgccga gattgtcaat aacggtcaca cgatccagct caacttcgac
     5881 gagggcgccg cgctgaaggt cgggccggac gtctggcggc tcgcgcaact gcatttccac
     5941 catccatgcg aacatctgat cgacgacaag gcctcggcga tggagatcca tttcgtccat
     6001 cgcaacgaaa aaggcctcgc cgtggtcggg gcgctggtca agcccggaaa atcaaatccg
     6061 acgtttcgaa agatcgtcgc cgccatgccg ggcgctgaag gtccggcgca gaaggcgccg
     6121 gcgggcttaa atccgcgcgg gcttctgccg aaagcgcgcg gctattttcg ttattccggc
     6181 tcgctgacga cgccgccctg cagcgaaacg gtcgattggc tggtgctgcg ccacccagtc
     6241 gaggttttga gcgcagatat cgacgctttc gcagagcttt acccgatgaa cgcgcggccg
     6301 gcgcagcaga tcgatcggcg cttcgtgctg cgatctgtct aggcgttttt gcgaggagga
     6361 gccagcgccg cctcagctgg aagagcgcgt cgctccacgc gccatgttga gttatcgcgc
     6421 gccgtcccga ccgccgttcc ggggctcgcg ccggcagccg ccatcgccat tgctttcacg
     6481 gccgcgcccg ctatagtccg gccgctccgg ggggacctgg aacgcatgtg caaagaggag
     6541 gcagagaatt gtttacccca gctttcgccc aggcggccgg cggcgcgggc ggcggagcga
     6601 cggatctgat cgtgcagctg atccccttcg cgctgatcct cgcgatcatg tatttcctca
     6661 tcatgcggcc gcagcagaag cgcgcccgcg aacatgccga cctcatcaag aatttgcgtc
     6721 gcggcgatag cgtcgtcacc tccggcggcc tgatcggcaa ggtgacgaaa gtcatcgacg
     6781 acgccgaggt cgagctcgaa atcgccccga atgtgcgggt ccgggtggcg cgcggcctcg
     6841 tcacggacgt ccggtcgaag ggcgagcccg tcaaggacgc ggcgaactct taaacttaac
     6901 cttccgccgg gcgcagcgcg cgctcccgcc tgatcctccg gacgatctca aatctatgct
     6961 gcgtttcgcg acctggaaaa ttgtctcgat cgtgatgatg accgtcatcg cgctgctcct
     7021 catcgtgccg agcttgctcg ggccgcagag ccgcgcggcg ctgatggcgc atgcgccgag
     7081 cttcctgccg atccggccga tcgtcctcgg cctcgacctg cagggcggct cgcatgtctt
     7141 gctcgaagtc gacggccagt cggtcgtcaa gacgctgatc gacaatctgc gcgacagcgt
     7201 ccgccgcacc ctgcgcgaag agaaggcctc gatctccggc ggcattggcg tgctgccgcg
     7261 cggcgtgcag ctgcgcattc cggacgccgc cgagcgcgag cggatcatgc cgaagctgcg
     7321 cctgcttacg gctccggcga gcgccggcat ttccggcgtc ggcggcgcgt cggtcttcga
     7381 cgtcacggag acggccgacg gcctcatcca gttcacagtg accgaggcgg ggatcaaggc
     7441 caagatgcgc cgggcggtcg aacagtcgat cgaggttttg cgccggcgcg tcgacgccct
     7501 tggcaccacc gaaccgaata tccagcgcca gggcgacgac cgcgtgctgg tcgaagtgcc
     7561 gggcctgcag gatactggaa aactcaagga aatcctcggc acgactgcga agcttgagtt
     7621 tcgtctcgtt tccgacaccg gcgccgaccc cgccgagacg gaaatgctcg aagaggtcga
     7681 acggccgggc tcgaagcttc ccgtgcagaa gcgcgtgatg gtgcagggcg aggatctgac
     7741 cgacgcccag cccggcttcg accagcgcac gcaggagccc gtcgtcaatt tccgcttcaa
     7801 tattcgcggc ggccagcgct tcggcgaggt cacttccgaa aatgtcgggc gccccttcgc
     7861 catcgtgctc gatggcaagg tgatttcggc gccgcgcatt ctcgggccga ttaccggcgg
     7921 ctccgggcag atctcgggcc acttcaccgt ggaatccgcc aataatctcg cgatcctgct
     7981 gcgcgccggc gcgcttccgg ccaagctcac catcgtcgag gagcgcacgg tcgggccggg
     8041 ccttggccag gattcaatcg acgccggcaa gcgcgcggcc tatgtcggcg cggcgctggt
     8101 cgcttgctat atgctgatca cctacgggat tttcggcgtc ttcgccaaca tcgcgctgtt
     8161 cgttcacatc gctttcattt ttgcgggtct cgtgttgctt ggcgcgacgc tgacgcttcc
     8221 cggcatcgcc ggcatcgttc tcaccatcgg catggcggtc gattccaatg tgctgatcta
     8281 tgagcgcatc cgcgaggaat cgcatgccgg ccgctcgatc gtctcctcgc tcgacgccgg
     8341 cttcaagcgc gccttcgcga ccatcgtcga ttccaacgtc accatgttcg tcgccgccgc
     8401 gatcctgtat tttctgggat ctggcccggt gcgcggcttc gccgtgtcgc tcgcgctcgg
     8461 cattttaacg accatcgtga cggcggtgac catgacgcgc atgatgatca cgctgtggta
     8521 tcgctacaag cggccggtca agctgccgat ttgaatcggc gcggccgctc aggcaaaggg
     8581 ctcttcgaga tgaaacttct gcgcctcgcg ccagagaaca ccaaattccc gttcatgcgc
     8641 ttccggcgca tcagctatcc gttctcggcg gtgatgtcga tcatttcggt cgtgctgttc
     8701 ctgacgctcg gcatgaattt cggcatcgat ttttccggcg gcacgctggt cgaattgcgc
     8761 gccaaatcgg gagccgcgga catcgcccag ctgcgcgcga tcgccgaaaa catgcatgtc
     8821 ggcgaggtcg aggtgcaggg cttcggccaa ccctcggacg tcacgctgcg ttttggcgtc
     8881 cagcatagcg aacagggcga cgccgcggcg caggaggcgg cgatcgcgcg cgtgaaggac
     8941 gcggtcggaa atgactacga gttccgccgc gtcgaggtcg tcgggccgcg cgtgtcgggc
     9001 gaacttgtgc aatccggcac gcttggcgtc gttgtcgcga tcgtcgccgt gctctgctat
     9061 ctttggttcc gcttcgagtg gcaattcgcc gtcggcgcga tcatcgccac catgcatgat
     9121 ttgttgctga cggttggctt cttctcgctg acaaggctcg aattcaacac gacgtcgatc
     9181 gcggcgatcc tgaccatcgt cggctattcg ctgaacgaga ctgtcgtcgt gctcgaccgc
     9241 atccgcgaaa tgatgcgcaa ataccgcaag atgccgaccg acgagctgat cgatctctcg
     9301 gtcaacgccg tgctgccgcg aaccatcatg actgcgacga ccgtgtttct cgcgcttttg
     9361 tccctggtgg tgttcggcgg ccaggtcatc cgttccttct cgatcgcgat gatctgggga
     9421 attttcgtcg ccacctattc atcggtcttc atctgctcgc cgatgctgat ctaccttggc
     9481 ctgcgcaatg agactgtcgg gcccgagccg acccccggcg gcaagctcgc caagaatccg
     9541 gcctgatctg acgccgccgc gcaaccgccg ggacacgcca ctgcgctgcc gaagggcctg
     9601 cgatgccgac tgacgcgcac gagccgaaat gccccggttt cctgcccggc gcgcacgcca
     9661 tcgacggcta tggctccggc ggtttccgct tcggcggcat gtcgcatcgc ggttcgatcc
     9721 tggcgctgcc gtccggcgtc tatgcctgga gcgcgcttga accggccgac atcaccgccg
     9781 cctcgctcgg ccagctgttc gccgaggagc gcggcctgat cgagcatgtt ctgatcggcg
     9841 tcggcgtcgc gatgggttcg ctcgacgccg agctgaaacg ccggcttaac gctgccggca
     9901 tccgcgccga gccgatgcag acgggcgccg cggcgcgcac ctataatatt ctgctcggcg
     9961 agaagcggcg ggtcgccgcc gcgcttttgg cggttccctg atgagcgaag ctttgagcgc
    10021 cctcgacgcc gattacgcct attgcgagac gatcgtccgc cgcgacgacc cggaccgctg
    10081 gctggcgagc ctgtttctcc ccgaaggcaa gcgccgttac gcgcatgcgc tctatgcgtt
    10141 cagcctcgaa atcgcgcggg tgcgcgaggt cgtctccgag ccgatgctgg gcgaaattcg
    10201 ctttcaatgg tggcgcgagg cgctggagca gccggatcgc gaggatgtgc gcgcaaaccc
    10261 tgtcgccgcc gccgtgaccg acgtcctggt ccgctttgat ttgccgagcg aacatttgct
    10321 tcaattgatc gatgcgcggc agttcgatct gttcgacgat ccgatgcaga gcgtggacga
    10381 gcttgaggcc tacgccaggg cgacctcgtc caatctgttc tgcctgacgc cgatgatcct
    10441 tgagcccgag accccctcgt ccggattcgg cgccgccagc catggcggga ccgcttatgc
    10501 gctgactggc ctcttgcgcg cctttccgtg gcacgccgcg cgcggccaat gttacgttcc
    10561 gctcgacatt ctgcgccgcc acgggctgga gcgcgcggat gctgtctcgg ggcgggcgtc
    10621 gccggccctt ttggccgccc ttgaggagtt ccgcgctctc gcccggtcgc atcttgagat
    10681 tttcctgacc cggatcgaag ggctgcccga tttggcgcgc ccagccttcc tgccgatctg
    10741 cctctgcgag ccctatctga ggctcatgga ggggaagtgc tacgatcctt tcaagaccaa
    10801 tgtcgtcctg ccgcaatggc gccggcaatg ggcgctctgg cgggccgcta agcactggca
    10861 gtaaaaatcc gcatcgtcgc gggggctttt tgcgcaaaaa cggcgacggt ttagccagga
    10921 tcatggcggc gccggctttg ctggggcagt gcgcagcttg aacgcatctg ttcttgaaag
    10981 gagcccgacg tcatgcgcat ccagagcgaa ggccagccgc atgctggcga ggattttcat
    11041 ttttccgttt cgggcggcgc cggagccaag accctgaagg cctatatcga atataagacg
    11101 gtgctggaca tcagcttttc cggggacctt cagcaaacgc tcgcgatccc gtcgcaaacc
    11161 ggaaaattca cgctaaaact cctcgctcat gacggcgcag gggaaagcgc ggaaatgcgc
    11221 tatgtgatcg ccggcgagcc gccagcgccc tgaggcgcag gggcgggagg cgcatgcgcc
    11281 ccgtcccgca attgctttct tttcgctttc attgctagaa cagatccatg atcggaaccg
    11341 tccgaaaaaa ttccgcgctg cgaattacgc gcccggcccg cggctgatta tttcgcgcgg
    11401 ggccgggacc cttatcgctg ttccggcggc cagtccgcgc cgcgctcgca acgagcgcca
    11461 tcaaaccagc agacgcaacc atgaatgaga tcgagacggc gcgcggcgtt ttgcgcacgg
    11521 ccgaaggcaa gggcgggggc gaggccaagt ccggcccgga ttattccaag agcctctatc
    11581 tgccgcagac cgactttccg atgcgggccg gcctgccgaa gaaggagccg gagctgctcg
    11641 cccgctggcg ggagatcggc ctttacgagc gcatgcgcga ggcggcgcgc gggcggccga
    11701 aattcgtcct gcatgacggc cccccctacg ccaatggcga catccatatc ggccatgcgc
    11761 tgaacaagat cctcaaggat ctcatcgccc gctcgcagca gatgcttggg gccgacgcca
    11821 attatgtgcc gggctgggac tgccacggcc tgccgatcga atggaagatc gaggagcaat
    11881 atcgcgccaa gggccgcagc aaggacgagg tgccggtcaa tgaatttcgc cgcgaatgcc
    11941 gcgccttcgc cgagcattgg gtcgaaatcc agcgcgaaca gttcaagcgg ttaggagtca
    12001 atggcgattg ggatcatccc tatctgacca tgacctatcc cgccgaggcg acgatcgccc
    12061 gcgagatcat gaaattcgcc gagaacgggc tgctctatcg cggctcgaag ccggtgatgt
    12121 ggagcgtcgt cgaaaaaacc gctctggccg aagccgaggt ggagtacgag gaccacgtca
    12181 gcgattgggt gtttgtggcg tttccggtga agcgcgttgg cgcggtcggt ctgccggaag
    12241 acattgtgcc gggcgtcgtg tctgcccatc ccaacaacga tgctcttgaa aaggcatcta
    12301 tagtcatctg gactacgacg ccctggacag taccggctaa tcgagcgatc agcttttcag
    12361 caaaaattcc ctatgggctg tatcgcatga cgctggcgcc cgaaggaaac tgggctccaa
    12421 tcggggcaac gtatttgctc gcggacgccc tcgctgatgg tgtattcaaa tctgcaaaag
    12481 ttgagagcta tgaaaaggtc tgcgacgttc cgccggacta ccttcgggct ttgacggccg
    12541 ctcacccatt cgctgcgact attcccggct acgaattcgc ggttccgctt tttgatggcg
    12601 atcacgttac cgccgacacc ggcacaggct tcgtccatac cgcgcctggc cacggccgcg
    12661 acgattatga tatctggacg tcacataagc gctttctgga agagcgcggc atcgacacgc
    12721 gcatcccgtt taccgtcgac gcggacggct ttttgacgag ggaggcgccg ggttttgccc
    12781 gccatcgcgt catcgacgac aagggcaaca agggcgacgc caatgaggcg gtcatcaagg
    12841 cgctgatcga ggccggcaat cttctcgcgc ggggcaggct gaagcaccaa tatccgcata
    12901 gctggcgctc gaaaaagccg ctgatcttcc gcaacacgcc gcaatggttc atcgcgctcg
    12961 acaaggattt cgagcttccg caatatcccc ttacttcccc acaaaatccc ctcaccctga
    13021 ggagcgggca aagcccgcgt ctcgaagggc gaggggatgg cgctagcttg gcgacccggg
    13081 cgccctcgtc cttcgagacg ccgcctacta cggcgtctcc tcaggatgag ggctttgcgc
    13141 cgaccctgcg cgcgatcgcg cttgccgaga ttgccaagac caaatgggtc cctgccgccg
    13201 gcgaaaaccg catcaccggc atgatcgcca atcgccccga ttgggtcgtc tcgcgccagc
    13261 gcgcatgggg cgtgccgatt gcgatctttg tcaacaagga gagcggcgac atcctgaagg
    13321 atcgtcaggt caacgcccgc atcacggagg cttttgccgc tgagggggcc gacgcctggt
    13381 tcgcggaggg cgccaaggcg cgcttcctcg gcaacgctca caaccccgaa gcttttgaaa
    13441 aaatcgacga cgtgctggac gtctggttcg attccggctc gacgcacgcc tttacgctcg
    13501 acgatccgca aaactttccg ggccttgccg gcatccggcg caagcgcgac ggcggcgatg
    13561 acgagatcat gtatctcgaa ggctccgacc agcatcgcgg ctggttccat tcctccctgc
    13621 tcgaatcctg cggcacgcgc ggccgcgcgc ccttcgatct cgtcctgacc catggcttcg
    13681 tcctcgacga gaagggtcag aaaatgtcga agagccaggg caacgtcacc gcgccgcaga
    13741 cgatcatcaa ggacgccggc gccgatattc tgcgcctctg ggtcgccgcc tccgactatt
    13801 ccgacgatct gcgcatcggt cccgagatcc tcaagacctt cattgagacc tatcgcaagc
    13861 tgcgcaacac catccgctgg atgctcggca cgctcgccca ttacgagccg gagcgcgccg
    13921 tcgccgtcga gcagatggag gagctggagc ggctgatgct gcaccggctg aaagagctcg
    13981 acgaggatat ccgggacgcc taccagcgct tcgatctgaa gcgcgtcgtg gcgcggctgt
    14041 cgtccttcct caattcggat ctgtcggcgt tttatttcga tatccgcaag gatgcgcttt
    14101 attgcgagcc gccctccagc ctgaagcggc tggcggcgct gaccgcgatc gagcagattt
    14161 ttcgcgccgt cacgctgtgg ctggcgccca tcctcgtctt caccagcgag gaggcgtggt
    14221 tgtcgcgcta ccgtgaaaaa atctccatcc atctcgaaac gctgcccgat cttccggacg
    14281 agtggcgcga cgaggcgctg gtcgtcaaat ggggaaagat ccgccgcatc cgcagcgtcg
    14341 tcaccgctgc gctggagatc gagcgcgcgc aaaagcgcat cggctcctcc ctggaagccg
    14401 cgccgcaggt gttcatcgcc gatcccgacc tgaagagcgc gctcgaaggc gtcgatttcg
    14461 ccgaaatctg cattgcgtcc gatatttcca tcgcggacgg cgaggggcct attgacgcgt
    14521 tccggctcga tgaggttccg ggcgtcgccg tcgttccgcg ccgcgccgag gggcgcaaat
    14581 gcgccagatc ctggcgcatc tcgccgctgg tcggctccga tcccgactat cccgacgtga
    14641 cgccgcgcga cgcgcgggcg ctgcgcgaac tccaggcggc gggactttgg ccgtgagccc
    14701 acgcgttctt ggggcgctcg tcgccgccct gaccctcgcg gccgatcagg ctaacaagct
    14761 ctggctgatc ttcgtctatg gcatcgaaca gcgccagccg atcgcgctgg cccccttcct
    14821 cgatgtcgtc tacgccaaaa atccgggcat ttcctattcg ctgctcagcg cccggaccga
    14881 ttttcagcgc tacgctttgc tgggcctcac cctcgccgcc acgatcttca tgatcctctg
    14941 gctgtggcgt tcgacctcaa agctgatcgc ctgcgcgctc ggtttgatta tcggcggcgc
    15001 gcttggcaac gcctatgatc gcgcggccta cggcttcgtg gccgatttct atcatttcca
    15061 cgtcggctcc ttctcctggt atgtgttcaa cctcgccgat gcggcgatcg tcgccggcgt
    15121 cgctttgctc ctttatgatt ccctgttcag cgcccgcggc gcggggacag gcggcaaaag
    15181 ccggggcgag ggcgcttcgg cgctatagaa attttaacgg ttttctgccc ctaaattgcc
    15241 cttatggcgc ccgatggtcc gtggcgagcg agcagtctgt cgctgaggat ttaagtttat
    15301 ggcatcgaac aggatgagcg ccgaccgtgt gcggctcctt cggcttctcg ccgtcagtct
    15361 cgccttctcc ggcctcgccg gcttcagccc ggcccgcgcg caggcgccgc aggaagacac
    15421 caatccgctg aactcggttc tcggcttcat cggcatgcag ttcgacaagg accgcgaatc
    15481 gatcgattat cgggcgcggg cgccgatcgt cgtgccgccc cgcaccgatc tgccgaagcc
    15541 caaagtcgcc tcgcgcgatg cgtcctggcc gagcgatccc gatatcggcg agcgccgcca
    15601 tgccgccgcc gaagcgcaaa ggcccgcgcc gcagctgacg ccgcaggcgc gcgtcgaatt
    15661 gtctccggcg gaactcgctg gcggcgtcgg cggccacgcg accgacgcgc cgcgcgcggc
    15721 ggaggacgat tgtcagccgg gcgccggcac gccgatctgc ctctacacgc cttggaaagc
    15781 gctgcaaagc atggtcggtc tcggcggcgg atcgtcgccc gacaaggtcg atcccggcgt
    15841 cgagccggat cgccgctatc tgaccgaacc gccaattggc tatcgcaagg cgaccgccgc
    15901 cgccgcggcg accatcgacg cgccgaagga tcagccggac tccagcgacg cgcaggctta
    15961 taaccgctcg caacggcaca agagttcagt cgacgaatga gattctgcta gcgtcggcga
    16021 cgccgacgct atggaagcca atcgcgacga ccgccgaaat cggcggctgg cgcttcacgc
    16081 gcctgccctg cgccgccttt ttgcgatcgc ggcgctccca agcgagcctt gatgtcgccc
    16141 cgcctcagcc cctcgacgca ggccaaaccg cgcggcggcc ttgctaaagg acggcgccct
    16201 ttctaagttt gctttgcctc cgccgctccc cttccgtcga tttgggggca aggggcgcgc
    16261 ggccgaattt cagaaagcgg tgtcccgatg tccttcgccc ctccccaagc atcttccctc
    16321 acgccatcgg cggaggcgcc ggcgaagcct agcggacccg tgatcggcca ggcgaaactc
    16381 gccaatggcc tcgagatcgt cgtgatcccc gatcaccgct cgccggtggt gacgcatatg
    16441 gtctggtacc gcaacggctc ggcggatgat ccgctcggca agtcgggcat cgcccatttc
    16501 cttgaacatc tgatgttcaa gggaaccagc acgcatcccc agggcgaatt ttcccagctc
    16561 gtcgccgatt ccggcggcca ggaaaacgcc ttcacctcca atgattacac cgcttatttc
    16621 cagcgcgtcg cgcgcgacca gctcgccgtc tgcatggaat atgaagccga ccgcatgaag
    16681 aatctggtgc tgaccgacga aatcgtcgcc cctgagcgcg aagtcgttct cgaagagcgc
    16741 cgcatgcgca ccgattcaga cccctccgat cagctcaacg aggcggtgca ggcggccctt
    16801 ttcacgcagc acccctatgg gcggccgatc atcggctgga accatgagat cgagagcctc
    16861 gaccgctccg atgcgctcgc ctattacgac cgtttctata cgccggagaa cgccattctc
    16921 gtcgtcgccg gggatgtttc gacggaggaa gtcgtcgaac tcgccgaaaa aatttacggg
    16981 ccgatcccgg cgcgcggcga gccgccgaaa cgggagcgtc cgcgcgagcc ggagcagcgc
    17041 gcccatcgcc ttgtcacgct ggccgacgag aaagttgagc agcccgcgca tcatggcgtc
    17101 tatctggtgc cgtcctatca tacggcggcg cccggcgtcg ccgaggcgct ggaagtgctt
    17161 ggccatctgc ttggcgccgg ccacaccagc cttctgttca agaatctcgt gatcgatcag
    17221 aagatcgcgg tcggcgcggg cgcgcattat cttggctcgg ccgtcgacga tacgcgcttt
    17281 tatgtctacg ccgtgccggc ggaaggggtc tcgctcgagc ggcttgacgc tgcgatcgac
    17341 gagatcatcg cgcgcgtcgc ggccgaaggc gtcgatgaag ccgatttcaa gcgcgcaaag
    17401 acccgcctga tcgccgacgc cgtctatgcg caggacaatc aggcctctct cgcgcgctgg
    17461 tatggcgcgt cgctggcgac aggcctttcc atcgaagatg tgacgcaatg gccgcagcgc
    17521 atcgacgccg tggcgcgcga ggacgtgcgc caggcggcgc ggctgctcga caagaagcgc
    17581 agcgtgaccg gcttccttct gtcggcgccg gccggagacg aagctccgcg cgacgggctc
    17641 gaagcggcgc tgaccgcctg aaacctatcc tcttttcggc cgaagcccgt cgggcgcggc
    17701 cgctggaatc ttgtaaatga caccgaccgc agcccttgaa acgcctgccc cgctcaagcc
    17761 agccgaatcc cgttcacgcg ccgcgcaggt gcaaaaaatt gtctccagtg gcggagtcga
    17821 agcctggctc gttgaggatt acgccgttcc gctcgtcgcc gttgaattcg ccttcaaggg
    17881 cggcgcgtcg caagatcctg cgggcaagcc gggtacggcc aatcttctgt cggggctgct
    17941 cgacgaaggc gcgggtccct atgacgccga aggctttcat cgcgcgctgg acgaggacgc
    18001 gatcgaactc tccttctccg ccgatcgcga taattttcac ggccggctgc agactctctc
    18061 gcgcaatgtc gcgccggcct tctcgctgat gcggctcgcg gtcaatgagg cgcggcttga
    18121 cgacgagccg ttcaagcgcg tgtcgtcgca gatcgccgcc agcctcaagc gggaagtcaa
    18181 tgatcccgac catgtcgcga gccgcgcctt ccgcgaaaag gcctaccttg gccatcccta
    18241 tggacggccc gtgcgcggcg acctcgacgt gctgccgacc ttgacccgcg acgatcttgt
    18301 cgatctccgg acggcggttt ttgcgcgcga gacgctgaaa atcgccgtcg tcggcgcgat
    18361 cgacgctgag gcgctgaagc gccatctcga cgatgtgttc ggcgccctgc cgcaggcggc
    18421 ggggctgatc gcaacgcccg aggcggagtt cagcagcctg ggacagcgct ttgtcgtcga
    18481 cgtggacgtt ccgcaatcga caatccgctt cggccggccg ggcctcgccc aaagggatcc
    18541 cgatttcttc gcgggcatgg tggtcaacca tgtgctcggc ggcggcgtct tctcggcgcg
    18601 cctgttccgc gaggtgcgcg aaaagcgcgg ccttgcctat tcagtctatt cgcagcttct
    18661 gaactacgac catggcgcga tgctctatgg cggcacttcg accaagaatg agcgcgccgc
    18721 cgagtcgatg gcggtgatcg aggccgaaat ccgcaatctg tccgaggtcg gcccgactga
    18781 ggaagaactc gacaaggcga agaaatatct gatcggctct tatgcgctgc gcttcgacac
    18841 gtcgaccaag atcgcctcgc agctgcttca tctgcagacg gacggtttcg acgtcgatca
    18901 attggacgag cgcaatcgcc ggatcgcggc ggcgaccatg gaggacgcca agcgcgccgc
    18961 caagcgcctg ttcggcgacg ccagcctgct ggtggccgtg gcgggacgcc ctgtggggat
    19021 gtagagcggc cggccgcgag gcgtctcggc ctggtggaac gttagcaatc ccatggcgcg
    19081 caagaaaatt gcgttcgaat cgcctttccc gacgccggcg ttcgaaccgg agagccgggc
    19141 ggcgctgcgg aaagcgatgg aagaagcgcg gcgttgcggc cgcgacgatc tgtggcgcga
    19201 ggcgctccga aagctttgcg cgcttgatgg aatagacctt agcgatccgc tgcattgcag
    19261 tttttatgaa acgctcggcg cttatgaaca ggcgctgacc gagaaaaatg ggcgcacgac
    19321 gcgcgccagc cggacccggc aaaaaatcag aaacaaggga atcgtcggct gcctcgagga
    19381 ttgggctctg gcgcctgcgc cgaccgaggg gttcgagatg ctgatccgaa ccggccgggc
    19441 ggagctgacc ggcgaatttc tgctgctgcg atatccggat cgattttcgg acaaagccgt
    19501 cgccgccgcc agagcccggc tcgaacgcgc cgggatcgat ccgccttcgc cagcgccgac
    19561 tcgaccgaga gactgaaaag ctcaaggcca cgccttcaca tctgctttgc gccctcgcct
    19621 tcgccgggaa tcgaagcgtc gcccgcgccg agcgggcgtt gcatcagcac cgtatcgatc
    19681 cattggccaa gttttcgccc gaccgagcgc agcgtccctc tatgcgcgaa gccgaggttc
    19741 ttgtgcaggg cgatcgatcc tgcattgccg ctgtcgccga tcacggcgat catctgccgc
    19801 catgggcccg cctcgcagcg ttcaatgagc gctgcgagca gcatcgttcc aacgccgcgt
    19861 ccgccaaggc cgacagcgac atagaccgaa tcctcgatcg tatgccgata agcggttcgc
    19921 gcccgatatt ccgcagcgta gctgtagccg acgattgtcc cgtcgagcgc cgcaataaga
    19981 aagggcaggc cttgttccag cgcggcggcg cggcgcgcgg cgaattcgcc gattgtggga
    20041 ggcgtttcct caaacgtcgc gaggccatgc aggacgtgat gggcgtagat cgccaaggcc
    20101 ggcgccatat ccttctcatc cgcgtcgcgg atgatgagcc cgcaacccgg cggctgaccc
    20161 ggcgcgaagg tggatctctc catcattcgc ctttgacggg cagcccctgg ggcagcgcga
    20221 agacgagcag agcatcgccc tgcggatagc cccagatcgc gctgccgccg gcggcgacgg
    20281 cgatatattg ccggccgccg atcgcatagg aaatcggcgg cgcattgacg cccgcgccgc
    20341 agttgaaacg ccagagcagc gcgccggagg cggcgtcgaa ggcgtcgaaa aatccatttc
    20401 cctcgccggt aaagacaagt ccgcccgccg tcgccagcgc gccgccgacc aagggctgcg
    20461 gcgtttgatg gctccagaga atcttgccgt tttgcttgag atcgagcgcg gccaggacgc
    20521 cccaattcgg agcaatggcc ggctcggcgg tggtataggc gacgggcggc ttgccgtcat
    20581 gcgccggaag aacggcggtc ttgaatgtcg tcggcagatg catcgccgcg acataggcga
    20641 tccctttggc cgcatcgacg gcggccggcg accaattgac cccgccgccg acgccggggg
    20701 cgatcgtcac cccttcgggc gtcggcgccg tgaatagatt gtcctgcggg acgaaggcgt
    20761 ccgatttgaa cagaaatttg ccgtcgcgcc ggtcattgac gaaataccag ccgagcttgc
    20821 tcgcctgacc gacggcggga atgatctttc cgccgatctc gacg
//
