LOCUS       CP001280               20618 bp    DNA              UNK 01-JAN-1980
DEFINITION  Methylocella silvestris BL2, complete genome.
ACCESSION   CP001280
VERSION     CP001280.1
KEYWORDS    .
SOURCE      .
  ORGANISM  .
            .
FEATURES             Location/Qualifiers
     cluster         1..20618
                     /note="Cluster number: 1"
                     /note="Detection rule(s) for this cluster type:
                     hserlactone: (Autoind_synth);"
                     /clusterblast="2. CP000356_c2	Sphingopyxis alaskensis
                     RB2256, complete genome. (13% of genes show similarity)"
                     /clusterblast="3. DQ088847_c1	Uncultured bacterium
                     MedeBAC46A06 clone MedeBAC46A06, partial ... (5% of genes
                     show similarity)"
                     /clusterblast="4. EF100191_c1	Uncultured marine bacterium
                     HF10_25F10 genomic sequence. (5% of genes show similarity)"
                     /clusterblast="5. CP001016_c3	Beijerinckia indica subsp.
                     indica ATCC 9039, complete genome. (5% of genes show
                     similarity)"
                     /clusterblast="6. AJXZ01000049_c1	Nitratireductor
                     aquibiodomus RA22 Contig49, whole genome s... (5% of genes
                     show similarity)"
                     /clusterblast="7. CAAF010000017_c1	Mesorhizobium sp. STM
                     4661' WGS project data, contig ANY_... (8% of genes show
                     similarity)"
                     /clusterblast="8. AAXY01000029_c1	Marinobacter sp. ELB17
                     1101232001184, whole genome shotgun... (10% of genes show
                     similarity)"
                     /clusterblast="9. AJMK01000069_c1	Gamma proteobacterium
                     BDW918 contig00196, whole genome sho... (5% of genes show
                     similarity)"
                     /clusterblast="10. NZ_ARVV01000001_c1	Methyloversatilis sp.
                     RZ18-153 MetRZ18153DRAFT_Scaffol... (5% of genes show
                     similarity)"
                     /clusterblast="11. AFHG01000058_c1	Methyloversatilis
                     universalis FAM5 contig00076, whole gen... (5% of genes
                     show similarity)"
                     /product="hserlactone"
     gene            complement(843..1892)
                     /locus_tag="Msil_0090"
     CDS             complement(843..1892)
                     /locus_tag="Msil_0090"
                     /codon_start=1
                     /product="pseudouridine synthase, RluA family"
                     /transl_table=11
                     /note="TIGRFAM: pseudouridine synthase, RluA family; PFAM:
                     RNA-binding S4 domain protein; pseudouridine synthase;
                     KEGG: bid:Bind_1312 pseudouridine synthase, RluA family"
                     /note="smCOG: SMCOG1279:pseudouridine_synthase (Score:
                     226.5; E-value: 7.6e-69);"
                     /note="smCOG tree PNG image: smcogs/Msil_0090.png"
                     /db_xref="GI:217501663"
                     /db_xref="InterPro:IPR002942"
                     /db_xref="InterPro:IPR006145"
                     /db_xref="InterPro:IPR006224"
                     /db_xref="InterPro:IPR006225"
                     /translation="MSVQTYEVAEDEDGLRLDRWFKRRIPALSLSHLNKIVRTGQVRVD
                     GARVKTATRLAQGQNVRVPPLNLEAAPEAPVFRISEEDQRDLRQMILFEDKDLMVLNKP
                     YGLAVQGGSGMRRHIDGMLASLPNERGDRPVLVHRLDRDTSGVLLIAKTRKMAADLGEI
                     FRSRQAQKIYWALVEGVPKPAQGKISLFLAKGEGMDARGPRRSDEERASMEKMRVAKHG
                     DEDAQHSVTYYATVDTFSPRAAWLSMKPITGRTHQLRAHAEAIGHPIIGDPKYGLRPKT
                     DPRRNDPLRAIPETIERKLHLLARRLVLPHPRGGVLDVTAPLPPHMANSFETFGFDVKQ
                     YDPIEGAPE"
                     /protein_id="ACK49072.1"
     gene            complement(1948..2868)
                     /locus_tag="Msil_0091"
     CDS             complement(1948..2868)
                     /locus_tag="Msil_0091"
                     /codon_start=1
                     /product="efflux transporter, RND family, MFP subunit"
                     /transl_table=11
                     /note="TIGRFAM: efflux transporter, RND family, MFP
                     subunit; KEGG: bbt:BBta_0549 hypothetical protein"
                     /note="smCOG:
                     SMCOG1029:RND_family_efflux_transporter_MFP_subunit (Score:
                     94.8; E-value: 4.472e-28);"
                     /note="smCOG tree PNG image: smcogs/Msil_0091.png"
                     /db_xref="GI:217501664"
                     /db_xref="InterPro:IPR006143"
                     /db_xref="InterPro:IPR006162"
                     /translation="MTRSARLRAPTLGENFAAIKKRRESRGAIALLAAVALAGPLRAEP
                     ADRAMTVSVVKTKTQCFVDSMRLNGRIVARDESLVRPDVEGLQIVQVLVEDGASVTAGQ
                     PLAQLARPDWLPGLPTKATMTASASGLVVYGRLPVGMPASARGEPMFRIIRDGQLELLV
                     DLPLPALARIKPGQIAQIEALDESEFAGTVRLILPEVDPLTQQGRARIQLSSSAGLRLG
                     AFATAAIDAGQSCGPAAPLSSILYGPEGAIVQVVRDNRVETRRVKVGLFGGAEAEIREG
                     LAPGDVVVARAGAFLREGDIVRTVP"
                     /protein_id="ACK49073.1"
     sig_peptide     complement(2737..2868)
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.999) with cleavage site probability 0.995 at
                     residue 44"
                     /locus_tag="Msil_0091"
     gene            complement(2865..3284)
                     /locus_tag="Msil_0092"
     CDS             complement(2865..3284)
                     /locus_tag="Msil_0092"
                     /codon_start=1
                     /product="protein of unknown function DUF305"
                     /transl_table=11
                     /note="PFAM: protein of unknown function DUF305; KEGG:
                     pde:Pden_0926 protein of unknown function DUF305"
                     /db_xref="GI:217501665"
                     /db_xref="InterPro:IPR005183"
                     /translation="MPPRALPLLCLALLLGGAPAGVLAAEEAGGVTTHDHGGMKMDAPA
                     TGAGKDSADAGYMRAMSNMDKTMSAPMTGDADVDFVIMMLPHHQGAVDMAKVALDHAKD
                     PFVRKLAGDVVQSQEAEIAAMKQWLAAHQTKGKVH"
                     /protein_id="ACK49074.1"
     sig_peptide     complement(3210..3284)
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 1.000) with cleavage site probability 0.948 at
                     residue 25"
                     /locus_tag="Msil_0092"
     gene            complement(3391..3464)
                     /note="tRNA-Cys1"
                     /locus_tag="Msil_R0001"
     tRNA            complement(3391..3464)
                     /locus_tag="Msil_R0001"
                     /product="tRNA-Cys"
     gene            3729..3804
                     /note="tRNA-Asn1"
                     /locus_tag="Msil_R0002"
     tRNA            3729..3804
                     /locus_tag="Msil_R0002"
                     /product="tRNA-Asn"
     gene            4255..5487
                     /locus_tag="Msil_0093"
     CDS             4255..5487
                     /locus_tag="Msil_0093"
                     /codon_start=1
                     /product="polysaccharide export protein"
                     /transl_table=11
                     /note="PFAM: polysaccharide export protein; KEGG:
                     bid:Bind_1033 polysaccharide export protein"
                     /note="smCOG: SMCOG1186:polysaccharide_export_protein
                     (Score: 272.8; E-value: 5.8e-83);"
                     /note="smCOG tree PNG image: smcogs/Msil_0093.png"
                     /db_xref="GI:217501666"
                     /db_xref="InterPro:IPR003715"
                     /translation="MPGLRLSGITLLATALIGVGGCSFFPQDGPASVDVLSQKSDIVPY
                     GLVKLTPETVDILAAYEPKGLAGTFTDRRPASNIKFGVGDIVSTTVFEATAGGLFIPLD
                     AGARPGNFVTLPDQAVDDHGNISFPFAGVIRAAGRNNVEIQNEIVERIKNRAIEPQVII
                     TLAQQRTSLISVIGEVNTPLRFAVPATGAGDRILDAITRAGGIKGQGFSTWVMLERGGK
                     RATVPFENLVMNASNNIYIQPGDRIYVYQEQQKFIAFGATGALDAIGSQGEFNFDAWRI
                     NLAEAVAKAGGLQDARADASAVFLYRREPREVAKLLGVDTGRFAGDLVPVIFQVNLRDP
                     GGYFIATRTQMRNGDVIYVSNAQSNDLSKFFNFVNTVASASAVTTTAIVGVPTASAAIH
                     GHALAGAAVVQ"
                     /protein_id="ACK49075.1"
     gene            5838..7133
                     /locus_tag="Msil_0094"
     CDS             5838..7133
                     /locus_tag="Msil_0094"
                     /codon_start=1
                     /product="glycosyl transferase group 1"
                     /transl_table=11
                     /note="PFAM: glycosyl transferase group 1; KEGG:
                     bvi:Bcep1808_6510 glycosyl transferase"
                     /note="smCOG: SMCOG1045:glycosyl_transferase_group_1
                     (Score: 88.6; E-value: 8.3e-27);"
                     /note="smCOG tree PNG image: smcogs/Msil_0094.png"
                     /db_xref="GI:217501667"
                     /db_xref="InterPro:IPR001296"
                     /translation="MQISAADTNKRLKILIIGENYAPEMTGVGRFTGEIGAYLAEHGYD
                     VTAVAAPPHYPGWSVKPPFHAGRYARETRDGVAVLRCPILLRADMRGVWRLIAPVSFAL
                     TAAPVALWQIVTRRPDVVLCVEPTLAAAPIGLLGKIFGARVLLHVQDLEVDAAFAVGHL
                     QGGALKKAIFSIESWLLRRFDSLVTISGQMRKRLIEKGVAAERIGIVRNWVDLDQIRPL
                     EGSNGFRAELGLSAAFVVLYAGNIGAKQALEVVLDAARALGGAKAIHFVIAGDGPEKAR
                     LMRDYGGLPGVHFLPLQPEARLCELLNLADLHVLPQARGAADLVLPSKLGGMLASGKPV
                     LATADAGTELFEVLQGAAILVPAGDSAAMAAEISRLAADGAHPALGDGRRLAQMFARET
                     CLEQFRAWIDPAGVKSAPAGQHKLTHFPEAQP"
                     /protein_id="ACK49076.1"
     gene            7133..7885
                     /locus_tag="Msil_0095"
     CDS             7133..7885
                     /locus_tag="Msil_0095"
                     /codon_start=1
                     /product="protein of unknown function DUF159"
                     /transl_table=11
                     /note="PFAM: protein of unknown function DUF159; KEGG:
                     bid:Bind_2022 protein of unknown function DUF159"
                     /db_xref="GI:217501668"
                     /db_xref="InterPro:IPR003738"
                     /translation="MCGRFAMTSPPEATRRFFGYLEQPNFPPRYNIAPTQPVPIVRGRF
                     DADHRLERCFDLVRWEFLPRFAKDPRNFPLIINARAETLLEKPSFAAAFRRRRCLFIAD
                     AFYEWRREAGSRGRGARPYLFRRADGAPLALGGIWESWCGPNGEELDTACIITTAANGS
                     TAAIHDRLPAIIARESFETWLCPDEATTEAALSQLRPPENDALEFFAIGPEVNKAANDY
                     KELQEPVAGAAPPSAPAQQDDPPQQLLF"
                     /protein_id="ACK49077.1"
     gene            complement(7987..8577)
                     /locus_tag="Msil_0096"
     CDS             complement(7987..8577)
                     /locus_tag="Msil_0096"
                     /codon_start=1
                     /product="transcriptional regulator, TetR family"
                     /transl_table=11
                     /note="PFAM: regulatory protein TetR; KEGG: bbt:BBta_2216
                     TetR family transcriptional regulator"
                     /note="smCOG:
                     SMCOG1057:TetR_family_transcriptional_regulator (Score:
                     82.8; E-value: 6.9e-25);"
                     /note="smCOG tree PNG image: smcogs/Msil_0096.png"
                     /db_xref="GI:217501669"
                     /db_xref="InterPro:IPR001647"
                     /translation="MKIVSEQKETDPHQNIVEVAERLFSQIGFQKTTVADIARELRMSP
                     ANVYRFFSAKAEINEAVGRRLLTETEASLEAISTQPGSASEKLRSAIAALEKANAQRFV
                     ANRKLHELLETAFNENWPIVQDHSKKLNKVLTNIISEGNSAGEFHVSDCELAAILVRSA
                     CIRFCHPRLMVECAQEPEPTLDQMVDFCLVALG"
                     /protein_id="ACK49078.1"
     gene            8993..9727
                     /locus_tag="Msil_0097"
     CDS             8993..9727
                     /locus_tag="Msil_0097"
                     /codon_start=1
                     /product="transcriptional regulator, LuxR family"
                     /transl_table=11
                     /note="PFAM: regulatory protein LuxR; Autoinducer-binding
                     domain protein; KEGG: bid:Bind_0920 transcriptional
                     regulator, LuxR family"
                     /note="smCOG:
                     SMCOG1197:autoinducer-binding_transcriptional_regulator,
                     (Score: 154.6; E-value: 4.6e-47);"
                     /note="smCOG tree PNG image: smcogs/Msil_0097.png"
                     /db_xref="GI:217501670"
                     /db_xref="InterPro:IPR000792"
                     /db_xref="InterPro:IPR005143"
                     /translation="MQGLEDVDIRTLLQLETDLSDETLDGFIEYIRHHYGLANIAYLCP
                     SFRGRSVADPFMALTYREEWVEHYKDEGYGLIDPVHNIGARSVLPLDWARLPRAEKKVQ
                     RMFGEAADAGVGRQGLTIPVRGPTNGLWALFSVTSDEADTEWARRRFELTKDMVHIAHY
                     VHQRAYKLHAKEDEIDLNAITKREIEALEWSAEGKSLADISILMRISVETVKAHLDSAR
                     YKLCALNRVHAVTKAIRAGLIR"
                     /protein_id="ACK49079.1"
     gene            10001..10618
                     /locus_tag="Msil_0098"
     CDS             10001..10618
                     /locus_tag="Msil_0098"
                     /codon_start=1
                     /product="autoinducer synthesis protein"
                     /transl_table=11
                     /note="PFAM: autoinducer synthesis protein; KEGG:
                     bid:Bind_0919 autoinducer synthesis protein"
                     /db_xref="GI:217501671"
                     /db_xref="InterPro:IPR001690"
                     /sec_met="Type: hserlactone"
                     /sec_met="Domains detected: Autoind_synth (E-value:
                     1.6e-27, bitscore: 93.9, seeds: 13)"
                     /sec_met="Kind: biosynthetic"
                     /translation="MITVVYGYEREERRDLFEEMFRQRKQVFVDEKKWDLKITDGEFEI
                     DEYDRDDTVYVCSLRPDGSLAGSVRLLNTLTDHMANGPFKEMFPELTVRSPTIWEATRF
                     AVPDDPRIQPNGVSRAACEIMLGTCLFGLEHGVSQLIAIYEAPMARVYRKCGVRHYVLG
                     RHRSAEAGSIHFALGEVSRQLEASIREATGLTPVETVVEAAE"
                     /protein_id="ACK49080.1"
     sig_peptide     10977..11042
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.999) with cleavage site probability 0.931 at
                     residue 22"
                     /locus_tag="Msil_0099"
     gene            10977..11729
                     /locus_tag="Msil_0099"
     CDS             10977..11729
                     /locus_tag="Msil_0099"
                     /codon_start=1
                     /product="protein of unknown function DUF81"
                     /transl_table=11
                     /note="PFAM: protein of unknown function DUF81; KEGG:
                     bbt:BBta_4771 hypothetical protein"
                     /db_xref="GI:217501672"
                     /db_xref="InterPro:IPR002781"
                     /translation="MLAIAIVALAAFAAGFINALAGGGSFLTLPAFIAAGVPPIAANAS
                     STVALFPGQIATGLSARDGIAAAAKDPRINAPVLAAISLIGGLIGGLLLLVTPPAIFAR
                     LIPWLILFATVIFAGGNAIREDSKLFKLNTVGIYLAQALVSIYGGYFGGGIGILMLAAL
                     TLYGMRDIWLMNSLKILLAVLMNAAAVVTFIVAGLVYWQLTIVAGVAAIIGGYAGIHAA
                     RRLPTRIVKGFVIMIGLILTVLFFLKTP"
                     /protein_id="ACK49081.1"
     gene            11755..12741
                     /locus_tag="Msil_0100"
     CDS             11755..12741
                     /locus_tag="Msil_0100"
                     /codon_start=1
                     /product="NAD(P)H quinone oxidoreductase, PIG3 family"
                     /transl_table=11
                     /note="TIGRFAM: NAD(P)H quinone oxidoreductase, PIG3
                     family; PFAM: Alcohol dehydrogenase zinc-binding domain
                     protein; Alcohol dehydrogenase GroES domain protein; KEGG:
                     bid:Bind_1245 NAD(P)H quinone oxidoreductase, PIG3 family"
                     /note="smCOG:
                     SMCOG1028:crotonyl-CoA_reductase_/_alcohol_dehydrogenase
                     (Score: 304.6; E-value: 1.3e-92);"
                     /db_xref="GI:217501673"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="InterPro:IPR014189"
                     /sec_met="NRPS/PKS subtype: PKS/NRPS-like protein"
                     /sec_met="NRPS/PKS Domain: PKS_ER (18-324). E-value:
                     2.2e-66. Score: 215.7;"
                     /sec_met="ASF-prediction: PKS_ER (18..324): Full match for
                     prediction: 2S"
                     /translation="MRYAYFDGAGGPEVIRIGEAARPAPGPGEVLIEVVAAGVNRPDCM
                     QRAGSYPPPPGESNIPGLEVAGRIVALGEGVTGFEAGDSVCALLGSGGYADYAVAAAPL
                     CLPAPQGLSFEEAAALPENVFTVYDNVFTRGRLAAGETFLVHGGSSGIGSIAIQLAKAS
                     GAIVIATAGSDAKCAFCRTLGADLSINYKTQDFAAETKAFAGEHGVDVILDMVGAPYLA
                     KNLSLLAFEGRLVEIACSGGGRVEAFNLWPVLIRRLTLTGSTLRARTLAQKAAVAAAVR
                     ERVWPLIEAGKVRPLVHATFPLEQTWAAHELMESSAHTGKIVLETGR"
                     /protein_id="ACK49082.1"
     aSDomain        11809..12726
                     /aSASF_choice="Description: ER domain putatively catalyzing
                     2S-configuration product formation, choice result: 2S,
                     choice coordinates: (39); residues: (Y); expected for
                     choice: (Y); matchArray: (True); emission probability array
                     (n.d.); overall match: TRUE"
                     /aSASF_choice="Description: ER domain putatively catalyzing
                     2R-configuration product formation, choice result: 2R,
                     choice coordinates: (39); residues: (Y); expected for
                     choice: ([^Y]); matchArray: (False); emission probability
                     array (n.d.); overall match: FALSE"
                     /domain="PKS_ER"
                     /database="nrpspksdomains.hmm"
                     /evalue="2.20E-66"
                     /locus_tag="Msil_0100"
                     /asDomain_id="nrpspksdomains_Msil_0100_Xdom01"
                     /detection="hmmscan"
                     /aSASF_prediction="Full match for prediction: 2S"
                     /score="215.7"
                     /aSASF_note="ASF analyisis with definition PKSI_ER_Stereo
                     (type prediction)"
                     /aSASF_scaffold="Scaffold coordinates:
                     (31,135,137,144,146,227); scaffold residues: (D,L,H,G,I,G);
                     expected: (D,L,H,G,A,G); matchArray:
                     (True,True,True,True,False,True); emission probability
                     array (n.d.,n.d.,n.d.,n.d.,n.d.,n.d.); overall match:
                     FALSE"
                     /translation="EAARPAPGPGEVLIEVVAAGVNRPDCMQRAGSYPPPPGESNIPGL
                     EVAGRIVALGEGVTGFEAGDSVCALLGSGGYADYAVAAAPLCLPAPQGLSFEEAAALPE
                     NVFTVYDNVFTRGRLAAGETFLVHGGSSGIGSIAIQLAKASGAIVIATAGSDAKCAFCR
                     TLGADLSINYKTQDFAAETKAFAGEHGVDVILDMVGAPYLAKNLSLLAFEGRLVEIACS
                     GGGRVEAFNLWPVLIRRLTLTGSTLRARTLAQKAAVAAAVRERVWPLIEAGKVRPLVHA
                     TFPLEQTWAAHELMESSAHTGKIVL"
     CDS_motif       11842..12234
                     /detection="hmmscan"
                     /locus_tag="Msil_0100"
                     /motif="PKSI-ER_m5"
                     /database="abmotifs"
                     /evalue="2.90E-04"
                     /asDomain_id="nrpspksmotif_Msil_0100_0001"
                     /note="NRPS/PKS Motif: PKSI-ER_m5 (e-value: 0.00029,
                     bit-score: 16.1)"
                     /score="16.1"
                     /aSTool="pksnrpsmotif"
                     /translation="VLIEVVAAGVNRPDCMQRAGSYPPPPGESNIPGLEVAGRIVALGE
                     GVTGFEAGDSVCALLGSGGYADYAVAAAPLCLPAPQGLSFEEAAALPENVFTVYDNVFT
                     RGRLAAGETFLVHGGSSGIGSIAIQLA"
                     /label="PKSI-ER_m5"
     CDS_motif       12244..12282
                     /detection="hmmscan"
                     /locus_tag="Msil_0100"
                     /motif="PKSI-ER_m6"
                     /database="abmotifs"
                     /evalue="2.30E-03"
                     /asDomain_id="nrpspksmotif_Msil_0100_0002"
                     /note="NRPS/PKS Motif: PKSI-ER_m6 (e-value: 0.0023,
                     bit-score: 10.9)"
                     /score="10.9"
                     /aSTool="pksnrpsmotif"
                     /translation="GAIVIATAGSDAK"
                     /label="PKSI-ER_m6"
     gene            12787..13131
                     /locus_tag="Msil_0101"
     CDS             12787..13131
                     /locus_tag="Msil_0101"
                     /codon_start=1
                     /product="regulatory protein ArsR"
                     /transl_table=11
                     /note="SMART: regulatory protein ArsR; KEGG: rpa:RPA2256
                     ArsR family transcriptional regulator ArsR1"
                     /note="smCOG:
                     SMCOG1058:ArsR_family_transcriptional_regulator (Score:
                     56.4; E-value: 4.96e-16);"
                     /note="smCOG tree PNG image: smcogs/Msil_0101.png"
                     /db_xref="GI:217501674"
                     /db_xref="InterPro:IPR001845"
                     /translation="MESDTAIESLAALAQATRLDVFRLLVRHEPDGLSAGEIARRLGVP
                     HNTLSTHFSVLARAGLIRSERQSRSIIYRADLGAIGRLAAYLVEDCCGGRPGACAPFLA
                     DLTRLEASEN"
                     /protein_id="ACK49083.1"
     gene            13165..13590
                     /locus_tag="Msil_0102"
     CDS             13165..13590
                     /locus_tag="Msil_0102"
                     /codon_start=1
                     /product="arsenate reductase"
                     /transl_table=11
                     /note="TIGRFAM: arsenate reductase; PFAM: arsenate
                     reductase and related; KEGG: nwi:Nwi_3125 arsenate
                     reductase"
                     /db_xref="GI:217501675"
                     /db_xref="InterPro:IPR006659"
                     /db_xref="InterPro:IPR006660"
                     /translation="MDVIIYHNPKCGTSRNVLGLIRNAGIEPHVIEYLKTPPTRLLISQ
                     LAARTGQPLRALLRDKEAIFASLGLDKPDVSDDALLDAIEKHPVLLNRPIVVSPKGVKL
                     CRPSELVLDLLPAQQGEFFKEDGERVVDEKGRHVASA"
                     /protein_id="ACK49084.1"
     sig_peptide     13632..13703
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.787) with cleavage site probability 0.684 at
                     residue 24"
                     /locus_tag="Msil_0103"
     gene            13632..14684
                     /locus_tag="Msil_0103"
     CDS             13632..14684
                     /locus_tag="Msil_0103"
                     /codon_start=1
                     /product="arsenical-resistance protein"
                     /transl_table=11
                     /note="TIGRFAM: arsenical-resistance protein; PFAM: Bile
                     acid:sodium symporter; KEGG: rpc:RPC_0616 bile acid:sodium
                     symporter"
                     /db_xref="GI:217501676"
                     /db_xref="InterPro:IPR002657"
                     /db_xref="InterPro:IPR004706"
                     /translation="MSFFERTLSLWVCACIVAGVILGQLAPGLFQAIGAIEIAKVNLPV
                     AALIWLMIVPMLLRIDFAALGEVRRHWRGMGVTLFINWAVKPFSMAALGWLFIGHFFRP
                     FLPADQIDSYIAGLILLAAAPCTAMVFVWSNLVKGEPHFTLSQVALNDVIMVVAFAPLV
                     GLLLGLSAIVVPWDTLALSVGLYIVIPVIAAQLARRALLAGGADAFARVLAILQPLSLA
                     ALLATLVLLFGFQGEQIAAQPLVILMLAAPILIQVYFNAGLAYLLNRIVGEPHCVAGPS
                     AMIGASNFFELAVAAAISLFGFRSGAALGTVVGVLIEVPAMLSLVYIVNASRGWYERAE
                     PAPAPRRAEG"
                     /protein_id="ACK49085.1"
     gene            14690..15394
                     /locus_tag="Msil_0104"
     CDS             14690..15394
                     /locus_tag="Msil_0104"
                     /codon_start=1
                     /product="arsenical resistance protein ArsH"
                     /transl_table=11
                     /note="TIGRFAM: arsenical resistance protein ArsH; PFAM:
                     NADPH-dependent FMN reductase; KEGG: nha:Nham_4428
                     NADPH-dependent FMN reductase"
                     /db_xref="GI:217501677"
                     /db_xref="InterPro:IPR005025"
                     /db_xref="InterPro:IPR014063"
                     /translation="MDELPNISPSAFEIPNADRLQTGKIRQPRILLLYGSLRQRSYSRF
                     LTLEAERLLKAFGAETRIYDPSGLPLPDDAPEMHPKVQELRDLSAWSEGQVWCSPERHG
                     AMTAIMKAQIDWIPLSIGAVRPTQGKTLALMQVSGGSQSFNAVNQLRVLGRWMRMITIP
                     NQSSVARAYEQFDEAGRMLPSPYYDRVVDVMEELVKFTLLTRGASAYLTDRYSERKEEA
                     EKLAARVGLHSI"
                     /protein_id="ACK49086.1"
     gene            15711..16328
                     /locus_tag="Msil_0105"
     CDS             15711..16328
                     /locus_tag="Msil_0105"
                     /codon_start=1
                     /product="RNA-binding S4 domain protein"
                     /transl_table=11
                     /note="PFAM: ribosomal protein S4; RNA-binding S4 domain
                     protein; KEGG: bid:Bind_1256 RNA-binding S4 domain protein"
                     /db_xref="GI:217501678"
                     /db_xref="InterPro:IPR001912"
                     /db_xref="InterPro:IPR002942"
                     /db_xref="InterPro:IPR005709"
                     /translation="MTKRAEAKYKIDRRMGQNIWGRPKSPVNRREYGPGQHGQRRKGKL
                     SDFGTQLKAKQKLKGYYGNISEKQFRKYYAEAIRLRGDSGDNLIGLLERRLDAVIYRAK
                     FVPTVFAARQFVNHGHVKVNGKRVNIASYLVKVGDVIEVKESSREILIVLEAKQLAERD
                     VPDYYEVDHNKMTAKITRIPLPADVPYPVLMEPNLVIEFYSR"
                     /protein_id="ACK49087.1"
     gene            complement(16513..18051)
                     /locus_tag="Msil_0106"
     CDS             complement(16513..18051)
                     /locus_tag="Msil_0106"
                     /codon_start=1
                     /product="AMP-dependent synthetase and ligase"
                     /transl_table=11
                     /note="PFAM: AMP-dependent synthetase and ligase; KEGG:
                     mpo:Mpop_2100 AMP-dependent synthetase and ligase"
                     /note="smCOG: SMCOG1002:AMP-dependent_synthetase_and_ligase
                     (Score: 360.7; E-value: 1.7e-109);"
                     /db_xref="GI:217501679"
                     /db_xref="InterPro:IPR000873"
                     /sec_met="Type: other"
                     /sec_met="Domains detected: AMP-binding (E-value: 1.4e-90,
                     bitscore: 301.6, seeds: 400)"
                     /sec_met="Kind: biosynthetic"
                     /sec_met="NRPS/PKS subtype: NRPS-like protein"
                     /sec_met="NRPS/PKS Domain: AMP-binding (36-439). E-value:
                     1.7e-92. Score: 301.6; NRPS/PKS Domain: Msil_0106_A1;
                     Substrate specificity predictions: asp,asn,glu,gln,aad
                     (NRPSPredictor2 SVM), N/A (Stachelhaus code), glu (Minowa),
                     nrp (consensus);"
                     /translation="MVWEYLEMTSVRTFEGLFAAGRGGDVAIAASNAAPLTFDGLRALV
                     AETIASLNGLGIGRNDRVAIVLPNGPEMATAFIAIASGSTSAPLNPSYKMDEFEFYMSD
                     LNAKALVVEAGSTSPAIEAAKKLNIPLVTLTPDAKRGAGYFTLSGEANGTAALPGRAEP
                     DDIALILHTSGTTSRPKIVPLTQANVAKSATNIAATVEFSEKDRGLNIMPLFHIHGLIA
                     GILAPLSRGGSVFCTPGFNALKFFAAMEEAKPTWYTAVPTMHQAILTRAANNKEIIARY
                     PLRFIRSSSSSMPPQVITELEATFHSPVIESYGMTEAAHQMASNPLHGVRKPGSVGLAA
                     GPEVAIMDETGGFLRAGEIGEIVIRGENVTAGYENNPKANAEAFTNGWFRTGDQGVMDE
                     GGYVTLTGRLKEIINRGGEKVSPREVDEALMDHPAVLQVVTFAVPHDKLGEDVAAAVVL
                     REGTTATEQELRAFLSERIAAFKTPRKILFLAEIPKGATGKLQRIGLAQKLGLA"
                     /protein_id="ACK49088.1"
     aSDomain        complement(16735..17943)
                     /domain="AMP-binding"
                     /database="nrpspksdomains.hmm"
                     /evalue="1.70E-92"
                     /specificity="NRPSpredictor2 SVM: asp,asn,glu,gln,aad"
                     /specificity="Stachelhaus code: N/A"
                     /specificity="Minowa: glu"
                     /specificity="consensus: nrp"
                     /locus_tag="Msil_0106"
                     /label="Msil_0106_A1"
                     /detection="hmmscan"
                     /score="301.6"
                     /aSASF_note="ASF analyisis with definition
                     StachelhausExtract (type active_site)"
                     /aSASF_scaffold="Scaffold coordinates:
                     (47,48,51,93,125,127,154,162,163); scaffold residues:
                     (I,H,A,T,R,S,S,H,Q); expected: (D,A,W,T,I,A,A,I,C);
                     matchArray:
                     (False,False,False,True,False,False,False,False,False);
                     emission probability array
                     (n.d.,n.d.,n.d.,n.d.,n.d.,n.d.,n.d.,n.d.,n.d.); overall
                     match: FALSE"
                     /translation="TFDGLRALVAETIASLNGLGIGRNDRVAIVLPNGPEMATAFIAIA
                     SGSTSAPLNPSYKMDEFEFYMSDLNAKALVVEAGSTSPAIEAAKKLNIPLVTLTPDAKR
                     GAGYFTLSGEANGTAALPGRAEPDDIALILHTSGTTSRPKIVPLTQANVAKSATNIAAT
                     VEFSEKDRGLNIMPLFHIHGLIAGILAPLSRGGSVFCTPGFNALKFFAAMEEAKPTWYT
                     AVPTMHQAILTRAANNKEIIARYPLRFIRSSSSSMPPQVITELEATFHSPVIESYGMTE
                     AAHQMASNPLHGVRKPGSVGLAAGPEVAIMDETGGFLRAGEIGEIVIRGENVTAGYENN
                     PKANAEAFTNGWFRTGDQGVMDEGGYVTLTGRLKEIINRGGEKVSPREVDEALMDHPAV
                     LQVV"
                     /asDomain_id="nrpspksdomains_Msil_0106_A1"
     CDS_motif       complement(16900..16983)
                     /detection="hmmscan"
                     /locus_tag="Msil_0106"
                     /motif="NRPS-A_a6"
                     /database="abmotifs"
                     /evalue="5.00E-08"
                     /asDomain_id="nrpspksmotif_Msil_0106_0003"
                     /note="NRPS/PKS Motif: NRPS-A_a6 (e-value: 5e-08,
                     bit-score: 25.3)"
                     /score="25.3"
                     /aSTool="pksnrpsmotif"
                     /translation="GEIGEIVIRGENVTAGYENNPKANAEAF"
                     /label="NRPS-A_a6"
     CDS_motif       complement(17497..17553)
                     /detection="hmmscan"
                     /locus_tag="Msil_0106"
                     /motif="NRPS-A_a3"
                     /database="abmotifs"
                     /evalue="2.40E-04"
                     /asDomain_id="nrpspksmotif_Msil_0106_0002"
                     /note="NRPS/PKS Motif: NRPS-A_a3 (e-value: 0.00024,
                     bit-score: 14.0)"
                     /score="14.0"
                     /aSTool="pksnrpsmotif"
                     /translation="ALILHTSGTTSRPKIVPLT"
                     /label="NRPS-A_a3"
     CDS_motif       complement(17788..17826)
                     /detection="hmmscan"
                     /locus_tag="Msil_0106"
                     /motif="NRPS-A_a3"
                     /database="abmotifs"
                     /evalue="2.70E+00"
                     /asDomain_id="nrpspksmotif_Msil_0106_0001"
                     /note="NRPS/PKS Motif: NRPS-A_a3 (e-value: 2.7, bit-score:
                     1.8)"
                     /score="1.8"
                     /aSTool="pksnrpsmotif"
                     /translation="AFIAIASGSTSAP"
                     /label="NRPS-A_a3"
     gene            complement(18070..19071)
                     /locus_tag="Msil_0107"
     CDS             complement(18070..19071)
                     /locus_tag="Msil_0107"
                     /codon_start=1
                     /product="2-dehydropantoate 2-reductase"
                     /EC_number="1.1.1.169"
                     /note="KEGG: pol:Bpro_2793 2-dehydropantoate 2-reductase;
                     TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: NADP
                     oxidoreductase coenzyme F420-dependent; Ketopantoate
                     reductase ApbA/PanE domain protein"
                     /db_xref="GI:217501680"
                     /db_xref="InterPro:IPR003710"
                     /db_xref="InterPro:IPR004455"
                     /db_xref="InterPro:IPR013332"
                     /db_xref="InterPro:IPR013752"
                     /translation="MKICVIGAGAIGGLLAAKLAHAGEEVSVIARGAHLLAIAKNGLTL
                     IEEGDKIVAPVAASDRIADLPQQDLIILGMKAHQVAAVVGDLPAIMGPKTTVLTAQNGI
                     PWWYFFGHGGPHEGVRLQSVDPGGIIADNLPIRHVIGSVVYPAAEIEKPGVIRHIEGNR
                     FSLGELDGSKSERITQVSEAFTKAGFKAPVVTDIRSELWTKLWGNLSFNPISALTHATL
                     EDICRFAPTRALAAEMMREAQTVGEALGIRFRISLEKRIAGAEAVGAHKTSMLQDVESG
                     RAIEADALIGSVIELGRTVGVATPHMDAVYALVKLLGETLTRAKGKLAVTPV"
                     /transl_table=11
                     /protein_id="ACK49089.1"
     sig_peptide     complement(19003..19071)
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.996) with cleavage site probability 0.995 at
                     residue 23"
                     /locus_tag="Msil_0107"
ORIGIN
        1 attgtagaac aatcgaagca gctttggatc ctcgggccaa ggcccatcat aggcgaagcc
       61 ttcaagcatt gcgatggcgc catccctgac gaaaaggata aaatctgcgc catttacgag
      121 tccctcaaca tctgccgaaa catttgtgat ttcgaggccg acagaatcag gaaggcgtgg
      181 cgcatcgggg ggaataaaaa agttggtaaa aaagcccact cctgcattct ctctttgagt
      241 tacttttgca ggcatatatt gctcacgcaa tattttgaaa ttggattcat ctccgcttag
      301 catcttttta agaatggcgg attcaatttg atttagtgtg tccatgggat aaacaccgat
      361 ccgattcgac gcttaccgtc aagaacgcga cctctgacaa tcacggaata aggtccgact
      421 tgcgtagtga cctcgtatcg ccggcgttga agagagcggt ggcgcgccgc agttttgcca
      481 gaaatgcgcg atggatgggt cgctgatagg ccgtggcgag cagcgccgcc gcgcgcgctt
      541 cgtcaaggac gagggagccg cccgccagcg tgtttttcca tacccgcgag aatgacgcga
      601 ggcccgagga cgattccctc gtcccggatc tccatccgac acgcgatccg gtccgcccgc
      661 gtccgttcct cgaatgcgcg cgaaatttcc tccgccagct ctgccaaatg ctccccctcg
      721 cgagatcggg attcgggtca gcagcttaag cgcaaacggc cgcatggcca aaacagacca
      781 tgaacaaatc agagaggaga gcgggtaagt ttggcggagg cgggctgcgc caagtccaaa
      841 aactattccg gcgcgccctc gatcgggtcg tactgcttga cgtcgaagcc gaacgtctcg
      901 aaggaattcg ccatatgcgg cggcagcggc gcggtgacgt ccaaaacgcc gccgcgcgga
      961 tgcggcagca ccaggcggcg cgccagcaga tgcagcttgc gctcgatggt ctcgggaatg
     1021 gcgcgcagcg gatcgttccg gcgtggatcg gttttgggcc gcagcccata tttgggatcg
     1081 ccgatgatcg gatggccgat cgcctcggca tgggcgcgca gctgatgcgt ccggccggtg
     1141 atcggcttca tcgacagcca ggcggcgcga ggcgaaaaag tatcgacggt ggcgtaatag
     1201 gtcaccgaat gctgcgcgtc ctcatcgcca tgtttggcga cgcgcatctt ttccatggaa
     1261 gcgcgctctt cgtcgctgcg ccgcggccct cgcgcatcca tgccctcgcc cttggcgaga
     1321 aaaagcgaga ttttgccctg cgccggtttc ggcacgccct cgaccagagc ccaatagatt
     1381 ttctgcgcct gccgcgagcg gaaaatttcg ccaaggtcgg cggccatttt gcgcgtcttg
     1441 gcgatcagca gcacgccgga ggtgtcgcga tcgagccgat gcaccagaac cggccggtcg
     1501 ccgcgctcgt tgggcaggga ggcgagcatg ccgtcgatgt ggcggcgcat gccggagccg
     1561 ccctgcacgg cgaggccata gggcttgttg aggaccatga gatccttgtc ctcgaacagg
     1621 atcatctggc gcagatcgcg ctgatcttct tcggaaatcc tgaacactgg ggcttccggc
     1681 gcggcttcga ggttgagcgg cggcaccctg acgttctggc cctgcgccag ccgcgtcgca
     1741 gttttcacgc gcgcgccgtc gacgcgcacc tgtcccgtgc ggacgatctt gtttagatgc
     1801 gagagcgaca gcgcgggaat gcggcgcttg aaccagcggt cgaggcgcag cccatcctca
     1861 tcttcggcga cttcatatgt ctggacgctc aaattttatg cctgttgcct caaatgcgcg
     1921 gcgcattttc gtggaaacga tcatgcgcta gggaactgtc cgcacaatgt ccccttcgcg
     1981 caaaaacgcg ccggcgcgcg cgacgacgac gtcgcccggc gcaagcccct cgcgaatctc
     2041 ggcctccgcg ccgccgaaca gcccgacctt gacccgccgc gtctcgacgc gattgtcgcg
     2101 cacgacctgc acgatagcgc cttccggccc gtaaagaata gaagaaagcg gcgccgccgg
     2161 gccgcagctc tggccggcgt cgatcgcagc cgtcgcgaag gcgccgagcc tcaggccggc
     2221 gctggagctg agctggatgc gcgcgcggcc ctgctgcgta agcggatcga cctcgggcag
     2281 gatgagccgc acggtgccgg cgaattcgct ctcgtcgaga gcctcgattt gcgcgatctg
     2341 cccgggtttg atccgggcca gcgccggcag cggcagatcg accaaaagtt cgagctgtcc
     2401 gtcgcgaatg atgcggaaca tcggctcgcc gcgtgcggac gccggcatgc cgaccggcag
     2461 ccgtccgtag acgacgaggc cgcttgcgct cgcggtcatc gtcgccttcg tcggcagtcc
     2521 cggcagccag tcgggccggg cgagctgcgc cagcggctgg ccggcggtca cgctcgcgcc
     2581 atcctcgacc agcacctgca cgatttgcag cccctcgacg tcgggccgca ctaggctctc
     2641 gtcccgcgcg acgatcctgc cgttcagccg catcgaatcg acaaagcatt gggtcttcgt
     2701 cttgacgacg ctgaccgtca tggcgcggtc ggccggctcg gcgcgcagcg gaccggcaag
     2761 agcgaccgcc gccagcagcg cgatggcgcc gcggctctcc cgacgcttct tgatcgcggc
     2821 gaaattttcg cccaacgttg gcgcacgcag cctcgccgat cgcgtcaatg gaccttccct
     2881 ttggtctgat gggccgcaag ccattgtttc atggcggcga tctcagcctc ctgcgactgc
     2941 acgacatcgc cggcgagctt gcgcacgaac ggatccttgg cgtgatccag cgcgaccttc
     3001 gccatatcca cggcgccttg atggtgcggc agcatcatga tgacgaaatc gacgtccgcg
     3061 tctccggtca tcggagcgct catcgtttta tccatgttgc tcatggccct catatagccg
     3121 gcgtcggccg agtccttgcc ggcgcccgtc gccggggcgt ccattttcat gccgccgtgg
     3181 tcgtgcgtcg tgaccccgcc tgcctcttcg gcggcgagga cgccggccgg cgcgccgcca
     3241 agcaggaggg cgagacaaag aagcggcaaa gcgcgaggcg gcatgtcatg aactccgggt
     3301 ttggcttgaa gcgcgccgca agggccgtcg cgcggcggcg aaggctcgcg gcctcgaaaa
     3361 tgcaatgata tcaagggttt gatgatgaat tggaggcctc gcccggaatc gaaccgggat
     3421 gcaaggattt gcagtcctct gcgtagccac tccgccacga ggcctccgtc gcgtcgaaag
     3481 cgcgccaccg gctatagcaa aggaagcggc taggaggcaa gaaatgttcg accgcgggcg
     3541 cgaaggccgc gaggggagct gcgagagggc gatttcgatt cccgtcgcgc ccgaatattg
     3601 gcgtccatgc gtcccggcgc gaggccgccc cgccgtcttg cgccggcaag ctggcgattc
     3661 gctctttgca acgggcggca agcttgctat atgccgcccg gtcgccgtgg cgtcttgccg
     3721 gcgcgtgatc cctgatagct cagctggtag agcaatcgac tgttaatcga tcggtcgcag
     3781 gttcgagtcc tgctcaggga gccatttcgg tacgaaactg cgaacgcatg catcgccgtt
     3841 tccactccag agcttcgtct ggacgccacg cgcgtctgga ggcgccttgg cttcgttccc
     3901 ttgatccggt tcatcggctg ctgcctccac ccgccgcagc ggggcggttg ggggcgcgcc
     3961 tccaggcccg gtcctgccgc agccgcacag gatcggctta tcgtagcggc cgactattgc
     4021 ggcgaggctg cgaagcaggc ccagcttcgc tcctcggaac ggcggctgcg ctacgcccat
     4081 cgcgcgttcg accctttgct gtccacttgg gaagaaccgg ctcgaccgcg gctgtgccaa
     4141 ttttgtaaca agttttgaca tactgcctgt caataaggcg gcaatcgtcc cgttgctcta
     4201 gtccgatcca cgccgtcagg gtatctgtca ggaaaggcgg agaggataga gttcatgccc
     4261 ggattgcgat tgagcggcat caccttactg gcgacagcgc tgatcggcgt cggcgggtgt
     4321 tccttcttcc cccaggacgg gccggcttcg gtcgatgtgc tgtcgcaaaa gtcggacatt
     4381 gttccctacg gcctcgtaaa gctcacgcct gagaccgtgg atattctcgc cgcctatgag
     4441 ccgaagggcc tcgccggcac cttcacggac cgtcgcccgg cgtccaacat caaatttggc
     4501 gtcggcgata tcgtctcgac gacggttttc gaggcgaccg ccggcggcct attcattccg
     4561 ctcgacgccg gcgcgcgccc cggcaatttc gtcaccctgc cggatcaggc ggtggacgac
     4621 catggcaata tttcgttccc tttcgccggc gtcatacgcg ccgcaggccg caacaacgtc
     4681 gagatccaga atgagatcgt cgaacggatc aaaaatcgcg cgatcgagcc tcaggtcatt
     4741 ataacgctgg cgcagcagcg gacttcgctg atcagcgtca tcggcgaagt aaatacgccg
     4801 ctgcgctttg ccgttccggc gacgggcgcc ggcgatcgca ttctcgacgc cattacccgc
     4861 gcgggaggca tcaaggggca gggcttctca acctgggtca tgctcgagcg cggcggtaaa
     4921 cgcgccaccg tgccgttcga aaatctggtc atgaatgcgt ccaacaacat ctatatccag
     4981 ccgggcgacc gtatttacgt ctatcaggag caacagaaat tcatcgcctt cggcgcgacc
     5041 ggcgccctcg acgcgatcgg tagccagggc gagtttaatt ttgacgcctg gcgcatcaat
     5101 ctggccgagg ccgtggctaa ggccggcggc ctgcaagacg cccgcgccga tgcgagcgcc
     5161 gtgttcttgt atcgcaggga gccgagggaa gtcgcaaaat tgctcggcgt cgatacgggc
     5221 cgctttgccg gcgatctggt gccggtcatc ttccaggtca atctgcgcga tccgggcggc
     5281 tatttcattg cgacgcggac gcaaatgcgc aacggcgacg tgatctacgt ctccaacgcc
     5341 cagtcgaatg atctcagcaa attcttcaac ttcgtcaata cggttgcctc agcgtcggcg
     5401 gtcacgacca cggccatcgt cggcgtgccg acagcttcgg cggcgattca tggccacgcg
     5461 ctggcgggcg ccgcagtcgt tcaatagcgc cctgcggctc gcgtcgcagg catgaggcga
     5521 agcgccgcgc ttccggtcca cgggaagatt cggcgcaacg cttgcatttg accgctcgat
     5581 tgaagatctt gccgttgaga tcttgccccc ccgcagggct tgcggcctca tggagcgact
     5641 ggcagagctg ttctgcgatc acgatgattt tgaattctca tccatccagg atcatgaaac
     5701 gtgatcgatc cttcggggtt agagcaggag gtcggttcga aagccttgct gctttccggc
     5761 gtcatgttct agccaagggg agctcgtcct ttgcgccttg agctgtttca gcccgcgtgt
     5821 cacttcgacg ggactcgatg cagatatctg ccgccgacac gaacaaacgc ctgaaaatct
     5881 tgatcatcgg cgagaattac gcgcctgaga tgaccggtgt tggccgattc acgggcgaga
     5941 tcggcgccta tcttgccgag catggctatg acgtcacggc ggtcgccgcg ccgccgcatt
     6001 atccgggctg gagcgtcaaa ccgccctttc acgcgggacg ctatgcgcgc gagaccagag
     6061 acggcgtcgc ggtgttgcgc tgcccgatct tgcttcgcgc ggatatgcgc ggcgtctggc
     6121 ggttgatcgc gccggtgagc tttgcgttga cggcggctcc tgtcgcgctc tggcagatcg
     6181 tgacgcggcg accggatgtc gtgctgtgcg tcgagccaac cctcgccgcc gcgccgatcg
     6241 gcctcctcgg caagatattc ggggcccgcg tgctgctgca tgtgcaggat ctcgaggtcg
     6301 acgccgcctt cgccgtcggc catttgcagg gtggggcgct gaagaaggcg atcttctcaa
     6361 ttgaatcctg gctgctgcgc cggttcgaca gcctggtcac gatttcgggc cagatgcgca
     6421 agcgccttat tgaaaagggc gttgccgccg aacgtatcgg catcgtccgc aattgggttg
     6481 atcttgacca gattcggccg ctcgaaggca gcaacggctt tcgcgcagag cttggtctga
     6541 gcgccgcttt cgttgttctt tacgccggca acatcggcgc taaacaggct cttgaggtgg
     6601 ttctcgacgc ggcgcgcgcg cttggcggcg caaaagccat ccattttgtc atcgccgggg
     6661 acggacccga gaaggcgcgg ctgatgcgcg actatggcgg cctccccggc gtgcattttc
     6721 tgccgttaca gcccgaggct cggctgtgcg aattgcttaa tctcgccgat ttgcatgtct
     6781 tgccgcaggc ccggggcgca gccgatctcg tcttaccctc aaagcttggc ggcatgctgg
     6841 caagcggcaa gcccgttctt gcgacggccg acgccggcac cgagctgttc gaggttctgc
     6901 agggcgccgc catattggtg ccggccggag acagcgcagc gatggccgcg gagatcagca
     6961 ggctcgcggc cgacggcgcg catccggcgc tgggcgatgg ccggcgtctt gcgcagatgt
     7021 tcgcgcgcga gacttgcctt gagcagtttc gcgcctggat cgatcctgcc ggcgtcaaat
     7081 ccgcccctgc gggccaacac aagctgaccc atttccccga agctcagccc tgatgtgcgg
     7141 tcgcttcgcc atgacctcgc cgcctgaggc gacgcggcgt ttcttcggct atctggagca
     7201 gcctaacttt ccgccgcgct acaatatcgc gccgacgcag cctgtgccga tcgtgcgcgg
     7261 gcgattcgac gccgaccatc gcctcgagcg ctgctttgat ctcgtacggt gggagttttt
     7321 gccgcgcttc gccaaggatc cgcgaaattt tccgttgatc atcaatgcgc gggcggaaac
     7381 cttgctggaa aaaccaagtt tcgccgccgc attccgccgc cgccgctgcc tgttcatcgc
     7441 cgacgcgttt tacgaatggc gccgcgaagc tggctcgcga gggcggggcg cgcgccctta
     7501 tctgttccgg cgcgccgatg gagcgcccct ggctcttggc ggaatttggg aaagctggtg
     7561 cggaccgaat ggcgaggagc tcgacacggc ctgcatcatc acgacggcgg cgaatggatc
     7621 gaccgccgcc attcacgacc gtctgcccgc aatcatcgcg cgcgaatcat ttgagacctg
     7681 gctttgcccg gacgaggcga cgactgaggc cgccctgagt cagttgcggc cgcccgaaaa
     7741 tgacgcgctc gaattctttg caatcgggcc ggaggtcaac aaagccgcga atgattataa
     7801 ggagctgcag gagccagtcg cgggagccgc gccgccgtcc gctccggcgc aacaggacga
     7861 tcctccgcaa caattattat tttagagctt tgagcgaagg ctgttgactg tcttgtcgag
     7921 aaaataattt aaaacaaaga cttgaagcgc tttccggccg aatgatccgg tcgacccagc
     7981 tctagcctag ccgagggcga caagacagaa gtcgaccatt tggtcgagcg tcggctccgg
     8041 ctcctgcgcg cattcgacca ttagtctcgg gtgacagaat cggatgcagg cgctgcgcac
     8101 cagaatcgcg gcaagctcgc aatcgctgac atggaattcc ccggcgctat tgccttccga
     8161 aatgatgttc gtcagcacct tgttaagctt cttcgaatga tcttgcacga tcggccagtt
     8221 ttcgttgaac gccgtctcga gcaattcatg cagcttgcgg ttggcgacaa agcgctgggc
     8281 gttcgccttt tcgagcgctg cgatggcgct gcggagtttt tcgcttgcgg agcccggctg
     8341 ggttgaaatg gcctcgagac tggcttcagt ctctgtcagc agtcgtcgtc cgaccgcctc
     8401 gtttatttcc gcttttgccg aaaaaaaacg atagacattg gcaggcgaca ttcgcagttc
     8461 acgggcgatg tccgcaacag tagtcttctg aaatccgatc tggctgaaca aacgctccgc
     8521 aacttccacg atattctggt gcggatcggt ttccttttgt tcgctgacga ttttcattct
     8581 atcgctatcc ccaattgaca gggaggacct tacaacgctt cggcatgaaa agcttcacct
     8641 atatgggaca caaatgcacg ttaacgtaac ctttgcagtt tgacttccac atctgcgcga
     8701 atcgtgaatt tccgccgtta tgcccgtaaa tagctgttgc gtcgagcgtt tcgcgctcgc
     8761 gaaagccgct tgtcaaaaga atttattgtt tattacaata ttcgctaccg acttgttcta
     8821 gataagtatt ttacgcgcta ttttgtcact ggtcagtgcg gcttctttaa cgttcactta
     8881 tcacaacaag agagccagca atcccgtcgc cgcgcatttg acggtttttt ctggcgttcg
     8941 cggagcggct gtgtgcaaat agtcgttaga ttaaattcgg gagcggtgcg gaatgcaggg
     9001 attagaggat gtcgacatca ggacgttgct ccagctggag accgacctaa gcgacgaaac
     9061 cctggatgga ttcattgaat atatccgtca ccactacggc ttggccaata tcgcttatct
     9121 ctgcccgtcc ttccgcggcc gctcggtcgc cgatcccttc atggcgctga catatcgcga
     9181 ggaatgggtc gaacactaca aggatgaagg ctacggcctg attgatcccg tccataatat
     9241 aggcgcccgc tcggttctgc cgctcgactg ggcgcggctg ccgcgcgccg agaagaaagt
     9301 gcagcggatg ttcggcgaag ccgccgacgc cggggtgggc aggcaggggc tgaccattcc
     9361 cgtccgcggt ccgaccaatg ggctctgggc tctgttcagc gttacttcgg acgaggccga
     9421 tacagaatgg gcgcgccgcc gattcgaact gaccaaggac atggtgcata tcgctcatta
     9481 tgtgcatcag cgggcctata agctgcacgc caaggaagat gagatcgatc tcaacgccat
     9541 caccaagcgg gagatcgagg cgctcgaatg gtcggcggaa ggcaaatcgc tcgccgatat
     9601 ctcgattttg atgcgcatct cggtcgaaac cgttaaggcg catcttgatt cggcgcgcta
     9661 caagctctgc gcgctgaatc gcgtccacgc ggtgaccaag gcgattcggg ccggcctgat
     9721 ccgatagacc actcagggct cgcggggtcg aactcgcaag ccagccgctg agcggaacag
     9781 gctcgttcgt tacgcgccct aagcaaattg ccgcacaggc gacattttct tcgatcatcg
     9841 aagcatccgg tgacgccttc agcatgaact ggggcgtggg atcggcggga gtcggttcat
     9901 aacgcacgtc ctgtgtgcgc cgcatatccc cgatcggggg aatatcctta aactcctgcc
     9961 gatagcatag ttgggcatcc acccgaacgg gagccctgat atgattactg ttgtttatgg
    10021 ttatgagcgc gaagagcgac gcgatctctt cgaggaaatg ttccgccagc gcaagcaagt
    10081 cttcgtcgac gaaaagaaat gggatctaaa gattactgac ggagaattcg agatcgacga
    10141 atatgaccgg gacgatacgg tctatgtctg cagcctgcgg ccggatggtt cgctcgctgg
    10201 ctcggtccgt cttttgaata cgttgaccga tcacatggcc aacgggcctt tcaaggagat
    10261 gtttccggaa ttgacggttc gctcgcccac gatctgggaa gcgacgcgtt tcgccgtgcc
    10321 ggacgacccg cgcatccaac ccaatggcgt gtcgcgcgcc gcctgcgaaa tcatgcttgg
    10381 aacatgcctg ttcggtctcg agcatggcgt gtcgcagctg atcgcgatct atgaggcgcc
    10441 gatggcgcgg gtttatcgca aatgcggcgt ccgccattat gtgctcggcc gtcatcgcag
    10501 cgcggaagcc ggctccatcc atttcgctct tggcgaagtt tcccgccagc tcgaagcttc
    10561 gatccgggag gccactggcc tcacccccgt cgaaaccgtc gtcgaagccg cggaataagc
    10621 ggccggcgcc cggacggttg cgccgcgcag ccgtccgtcg aaagtccagg gcatcggcaa
    10681 acgcagcccc gctcggaagg cttcgccttt ccgggcggtt ggcgtctctg gcacgtggcc
    10741 cagacggagc ttgatttttc gtcatgctta cgccgccgat tttaaatcgc gcccggccgg
    10801 cggacgcctg atcccacgcg cgctcaggcg ctcgattgaa aaagaggcgg cgatcgatct
    10861 gaaagcgaga cggctttcct ctgaaacaat cgcgctctag aaagagccct tccgaggccg
    10921 cgctgaggcg gctgcgcgat cctcgtgcgc gctggcgcat cgaaagggcc tttttattgc
    10981 tcgcaatcgc tatcgtcgcg ctcgcggcct ttgcggccgg cttcatcaac gcccttgccg
    11041 gcggcggctc ctttctgacg ctgcccgcct tcatcgccgc gggcgttccg ccgattgccg
    11101 cgaacgcctc cagcacggtc gcgctgtttc ccggccagat cgccacgggt ttatccgcgc
    11161 gcgacggcat tgcggcggcg gcgaaggacc cccgcatcaa cgctccagtc ctcgcggcga
    11221 tcagccttat cggcggcctc attgggggcc tgctgctgct tgtcacgccg ccggcgattt
    11281 tcgcgcggct gattccctgg ctcattctgt ttgcaacagt cattttcgcg ggcggcaatg
    11341 cgatccgcga agatagcaag ctgtttaagc tgaatacggt cgggatctat ctcgcgcagg
    11401 cgttggtctc gatctacggc ggttatttcg gcggcggcat cggcattttg atgctcgccg
    11461 cgctgacgct ctacggcatg cgcgacatct ggctgatgaa cagcctcaaa atcctgctcg
    11521 ccgtgctgat gaacgccgcc gccgtcgtca ccttcatcgt cgccggtctc gtatattggc
    11581 aattgaccat cgtcgcgggg gtcgcggcga tcatcggcgg ctacgccggc atccacgcgg
    11641 cgcgccgcct gccgacgcgc attgtgaagg gtttcgtcat tatgataggg ctgattctca
    11701 ccgtcctgtt ctttctcaag acgccttgag ggccggacgg agatcgaggc tcgcatgcgc
    11761 tatgcctatt tcgacggagc aggcggtccg gaggtcatca ggattggcga ggcggcgagg
    11821 ccggctccgg ggcccggcga ggttctgatc gaagtcgtcg cggcgggcgt caaccgtccg
    11881 gactgcatgc agcgcgccgg ctcctatccg ccgccgccgg gcgaatcgaa cattccgggg
    11941 cttgaggtcg ccggccgcat tgtcgctctt ggcgagggcg tgaccggttt tgaggctggc
    12001 gattcggtct gcgcgctgct tggttccggc ggctatgcgg attacgccgt cgccgccgcg
    12061 ccgctatgcc tgccggcgcc acagggcctc agcttcgaag aggcggcggc gctgccggaa
    12121 aatgtcttca ccgtctacga caatgtattt acgcgcgggc gcctggcggc cggcgagact
    12181 tttttggtcc atggcggctc ctccggcatc ggctcgatcg cgatccagct ggccaaggcc
    12241 tccggcgcaa ttgtcatcgc gacggcgggc tcggacgcca aatgcgcctt ctgccggacg
    12301 ctcggcgcgg atctctccat caattacaag acgcaggatt tcgcggccga gacgaaggct
    12361 tttgccggag agcacggcgt cgacgtcatt ctggacatgg tcggggcgcc ctatctcgcc
    12421 aaaaacctat cgcttcttgc cttcgagggc cggctggtcg agatcgcctg ctccggcggc
    12481 gggcgcgtcg aagcgttcaa tctctggccc gtgctgatcc gccgcctgac gctgaccggc
    12541 tcgaccttgc gcgcccgcac gctggcgcag aaagccgcag tcgccgctgc cgtgcgcgag
    12601 cgcgtatggc cgctgatcga agcgggcaag gtgcggccgc ttgttcatgc gacgtttccg
    12661 ctggaacaga cctgggccgc gcatgaattg atggaatcgt ccgcccacac cggcaagatc
    12721 gtgctcgaaa cagggcgcta ggcgactgcc gcttgtttat ttctatatgt cggctattat
    12781 cgacatatgg agagtgatac cgcgattgaa agtctggctg cgttggcgca agcgacgcgt
    12841 cttgatgtgt ttcgcttgtt ggtgaggcac gagcctgacg gcctttccgc tggcgaaatc
    12901 gctcgtcgcc tgggcgttcc gcataatacg ctttcgacgc atttttcggt tctcgcgcgg
    12961 gcggggctga tccgctccga acgtcagagc cgctcgatca tctaccgcgc cgatcttggg
    13021 gcaattgggc gcctggccgc ctatctcgtg gaggattgct gcggcgggcg tcccggcgcc
    13081 tgcgccccgt ttctcgccga cctgacgcgg ctcgaggcgt ctgaaaattg agacacagtt
    13141 gcaacctcga caaaggaatc cgtcatggat gtcatcatct accacaaccc caaatgcggc
    13201 acgtcgcgca acgtgcttgg cctcatccgc aacgctggta tagagccgca tgtcattgaa
    13261 tatttgaaaa cgccgccaac ccggctgttg atcagccagc ttgcggcgcg cacaggccag
    13321 ccgctgcgcg ccttgttgcg cgacaaggaa gcgatcttcg cgagccttgg cctcgataag
    13381 cccgatgtgt cggacgatgc gctgcttgac gccatcgaaa agcatcccgt gctgctcaac
    13441 cgccccatcg tggtttcgcc caagggcgtg aagctctgcc gcccctccga actcgtgctc
    13501 gatcttctgc cggcgcagca aggcgaattc ttcaaggaag acggcgagcg cgtcgtcgat
    13561 gaaaagggac gccacgtggc gagcgcctga cggcgcggat cgccgccgcg ggcgcccgca
    13621 ggaacatcaa catgtccttt tttgaacgca cgctctccct gtgggtatgc gcctgcatcg
    13681 ttgcgggcgt cattctcggc caattggcgc cggggctatt ccaggctatc ggcgcgatcg
    13741 aaatcgccaa ggtcaatctg cccgttgcgg cgctgatctg gctgatgatc gttcccatgc
    13801 tgctcaggat cgattttgcg gcgctcggcg aagtgcggcg tcattggcgc ggcatggggg
    13861 tgacgctgtt tatcaattgg gcggtgaagc ccttttcgat ggcggcgctc ggctggctgt
    13921 ttatcggcca ttttttccgg ccgtttctac cggccgatca aatcgactct tatattgcgg
    13981 gccttattct tctggccgcg gcgccctgca cggcgatggt tttcgtctgg tccaatctcg
    14041 tcaagggaga gccgcatttc accctgagtc aggtggcgct gaatgacgtc atcatggttg
    14101 tggctttcgc gcccctggtc gggcttctgc tcggcctgtc ggcgatcgtc gtgccatggg
    14161 acacgctcgc tttgtctgtc gggctctaca tcgtgattcc tgtcattgca gcgcaattgg
    14221 cccggcgcgc gctgcttgcc ggcggcgccg acgccttcgc gcgcgtcctg gccattctac
    14281 agccattgtc gcttgccgca ttgctcgcga ccttggtgct gttgttcggg ttccagggcg
    14341 agcagatcgc cgctcagccg ctggttattt tgatgctcgc cgcgccgatc ctgatccagg
    14401 tttatttcaa cgcggggctt gcctatctgc tcaatcggat cgtcggcgag ccgcattgcg
    14461 tcgccgggcc ctccgcgatg atcggcgcca gcaatttttt tgagctcgcc gtcgccgccg
    14521 cgatcagcct gtttggcttc cggtccggcg cggcgctggg gacggtcgtc ggcgtgctga
    14581 tcgaagtccc ggcgatgctg tctcttgtct atatcgtcaa cgccagccgc ggctggtatg
    14641 agcgcgcgga gccggcgccg gcgccgcgac gggcggaggg ataaatcgtt tggatgagtt
    14701 gccgaatatt tcgccctccg ctttcgagat ccccaacgcg gacaggctgc aaacaggcaa
    14761 gatacgccag ccgcgcattc tgttgctcta tggctccttg cggcagcggt cctacagccg
    14821 cttcctgacg cttgaagcgg agcgtctttt gaaggcgttt ggcgcggaaa cccggatcta
    14881 tgatccaagc ggattgccat tgccggacga tgcgcccgaa atgcacccga aggtccagga
    14941 attgcgcgac ctttcggcct ggtccgaagg gcaggtctgg tgctcgcccg agcggcatgg
    15001 cgccatgacc gccatcatga aagcgcagat cgactggatt ccgctctcga tcggcgcggt
    15061 tcggccgaca cagggaaaga ccctcgcgct gatgcaggtc agcggcggct cgcaatcctt
    15121 caatgcggtc aatcagcttc gcgtccttgg ccgctggatg cggatgatca ccattccgaa
    15181 ccaatcctcg gtggccaggg cctatgagca atttgacgaa gctggccgga tgcttccctc
    15241 gccttactat gatcgcgtgg tcgacgtgat ggaggaattg gtcaagttta cgcttctgac
    15301 ccgcggcgcc tccgcctatc tgacggaccg ctacagcgag cgcaaggagg aggcggaaaa
    15361 gctcgccgcg cgggtggggc ttcactcgat ttgagcgcgt cgccttgacg ggcccgcaaa
    15421 actcctttaa ccaacgccgc ttgccgcgct tttgcgcggt aaatttttgg gctggttttt
    15481 tccggtccta acgcacccgc ggcgcctctt cgcgaggtcc ggttcgccgg acctgtcatg
    15541 aagagcaggc gcctgtcggc tccgccaaaa aagcggtggg gcagaggagg gcgcgttcct
    15601 ccccctattg gcgggaggac gcgagttttg agcgccgcgc ttttcgataa agcgccgggc
    15661 gtttgcgcgc gcgtcctcat tgccgatgca atgatgatcg aggacacgcg atgacaaagc
    15721 gcgcagaagc aaaatataaa atcgaccgaa ggatgggcca gaatatctgg ggccgtccga
    15781 aaagccccgt caaccgccgc gaatatggcc ccggtcagca cggccagcgc cgcaagggca
    15841 agctctccga cttcggcacg cagctcaagg ccaagcagaa gctcaaaggc tattacggca
    15901 atatttcgga aaagcagttc cgcaaatatt acgccgaagc cattcgcctt cgcggcgact
    15961 cgggcgacaa tctgatcggg ttgctggagc gccggctcga cgcggtgatc taccgcgcca
    16021 aattcgtgcc gacggtgttc gccgcgcgcc agttcgtcaa ccatggccac gtcaaggtca
    16081 atggcaagcg cgtcaacatc gcttcctacc tcgtcaaggt cggcgatgtg atcgaggtca
    16141 aggaatcctc gcgcgagatc ctgatcgtgc tcgaggccaa gcagctcgcc gagcgcgacg
    16201 tgccggatta ttatgaggtc gatcataata agatgacggc gaagatcacg cgcattccgc
    16261 tgccggcgga cgtgccctat ccggttctga tggagccgaa tctggtgatc gaattttact
    16321 cgcgctaaat ctgcgccatc gatcgccgcc ttgccttgag caagacggcg aagtttttag
    16381 cggaccaatc gctttagcga acggtccgct tttttgtggg tcgattggat acgaagcggc
    16441 ggcaaattgc tttcgcaacc gccgccgcat ccacgccctg ttcgaaaaaa cccgtaggcg
    16501 cggaagttta aatcaggcga ggcccagttt ctgcgcgagg ccgatgcgct gcagctttcc
    16561 cgtcgcgcct ttcgggattt ccgctaaaaa caggatcttg cgcggcgtct tgaacgccgc
    16621 gatccgctcg gacagaaaag cgcgcagctc ctgctcggtc gccgtcgttc cctcgcgcaa
    16681 caccacagcc gcggccacat cctcgccgag cttgtcgtgc ggcacggcga atgtcacaac
    16741 ctgcaacacc gccgggtgat ccatcagggc ttcgtcgacc tcgcgcggcg agactttctc
    16801 gccgccccgg ttgatgatct ccttgaggcg cccggtcaga gtgacatagc cgccttcgtc
    16861 cattacgccc tgatcgccgg tgcggaacca gccgttcgtg aaagcctcgg cgttggcttt
    16921 cgggttgttt tcatagcccg cggtgacatt ctcgccgcgg atgacgattt cgccgatttc
    16981 gcctgcgcgg aggaagccgc cggtctcatc catgatggcg acttcaggcc ccgcggcaag
    17041 tcccacggag cccggctttc tgacgccatg caacgggttc gacgccatct gatgcgccgc
    17101 ttcggtcatg ccgtaggatt cgatcaccgg cgaatggaag gtcgcctcga gttcggtgat
    17161 gacctgcggc ggcatcgaag acgacgacga gcggatgaac cgcagcggat agcgcgcgat
    17221 gatttccttg ttgttcgctg cccgcgtcag gatcgcctga tgcatcgtcg gaaccgccgt
    17281 gtaccaggtg ggctttgctt cttccatcgc cgcgaagaat ttcagcgcat tgaagcccgg
    17341 cgtgcagaac acgctgccgc cgcgcgacag cggcgccaat atgccggcga tgaggccatg
    17401 gatgtggaac agcggcatga tattcagccc gcgatccttc tcggaaaact ccacggtcgc
    17461 cgcgatgttg gtcgccgatt tggcgacatt ggcctgcgtc agcggcacga ttttgggacg
    17521 cgacgtcgtg ccggaggtgt gcaggatcaa ggcgatatcg tcgggttcgg cgcggccggg
    17581 cagggcggcg gttccgttcg cttcgcctga gagcgtgaaa tagccggctc cgcgttttgc
    17641 atccggcgtc agcgtcacca gcggaatgtt gagcttcttc gccgcctcga tcgccggcga
    17701 cgtgcttccc gcctcgacca caagcgcctt ggcgttgaga tcgctcatgt agaattcgaa
    17761 ctcgtccatc ttgtaggatg gattgagcgg cgcggaggtc gagccggagg cgatcgcgat
    17821 gaacgccgtc gccatctccg ggccgttcgg caggacgatg gcgacgcggt cgttgcggcc
    17881 gatcccgagg ccgttcagcg aggcgatcgt ttccgcgaca agcgctcgga ggccgtcaaa
    17941 ggttaaaggc gcggcattgg aggccgcgat tgcgacgtcg ccgccgcgcc ctgccgcaaa
    18001 caatccctcg aatgtccgca ctgaggtcat ttccagatac tcccaaacca ttcaaattcc
    18061 gcggccgcct cacacgggcg tcacggcgag cttgcccttg gcgcgggtca gcgtttcgcc
    18121 cagcagctta accagcgcat agacggcgtc catatgaggc gtcgcgacgc cgactgtgcg
    18181 gccgagctcg atcacggagc cgatcagcgc gtcggcctcg atcgcgcgtc cgctttcgac
    18241 gtcctgcagc atcgacgttt tgtgcgcgcc gacggcttcg gcgccggcga tgcgcttttc
    18301 gagcgaaatg cggaatcgga tgccgagcgc ctcgccgacc gtctgcgcct cgcgcatcat
    18361 ctcggcggcc agcgcgcggg tcggcgcaaa gcggcaaatg tcttcgagag tcgcatgggt
    18421 cagcgcgctg atcggattga agctcagatt gccccagagc ttggtccaga gctcggagcg
    18481 aatatcggtg accaccggcg ccttgaagcc ggctttcgta aacgcctcgg agacttgcgt
    18541 gatccgctcg cttttggagc cgtcgagctc cccgagcgaa aaccggttgc cttcgatatg
    18601 gcggatgacg ccgggcttct cgatttcggc cgccggatag acgacgctgc cgatgacatg
    18661 gcggatcggc agattgtcgg cgatgatccc ccccggatcg acgctctgca agcgcacgcc
    18721 ttcatgcgga ccgccgtgcc cgaaaaagta ccaccatgga attccgttct gcgccgtcag
    18781 gaccgtggtc ttcgggccca tgatcgccgg caagtcgccg acgacggccg cgacctgatg
    18841 cgccttcatg ccgaggatga tcaggtcctg ctggggaagg tcggcgatgc ggtcggaggc
    18901 ggcgacgggc gcgacgatct tgtcgccctc ttcgatcagg gtcagcccat ttttcgcaat
    18961 ggccagaagg tgcgcgccac gcgcaatgac gctgacctct tcgccggcat gggcgagttt
    19021 ggcggcgagg aggccgccga tcgcgccggc gccgattacg cagattttca tcgatcgatt
    19081 tccattcgtc ctatcttgca ggggaatagc cgctttcgcg aagcgcgttc catgccggat
    19141 ccgccggcgt gatgtccagt ccgagaggtc gaaatcgcaa aaatctgcgc cgacgccgca
    19201 ggaagcgcaa aaatcggccg ctcggtcaat cccgaaaatt tccgctcagg cgcgcccgaa
    19261 gcttcaggag cccgctcccc atccccgctc aatcgtcgcg cagtttatgc cgcaatgcac
    19321 ccaagaggga ttctctttca accataatat tcttggcctt tcacaagaaa aaattgcttg
    19381 cccaaacttg ctgcggcaat caaaacttct gcgccagacg cgctctgggt tgtcagctga
    19441 ggatttgacc aagtggccga agagtctgtg ttggttggaa gtcgggccgc gccaaatcga
    19501 tggctgcagc ttgttttggg cgtgctctgc atgaccatga tcgccaacct gcaatatggc
    19561 tggaccctgt tcgtcaatcc catgcaggaa aagttcggct gggaccgctc cgctattcag
    19621 atcgctttca cgattttcat cgtcgccgaa acctggctcg tgccgctgca cgggtatgtc
    19681 gtcgacagga tgggaccaaa ggtcgtcgtc ctgctggccg ggttgctgtg cggcctcgcc
    19741 tgggtgctga attcgcaggc gacaagcctg cccatgctgt attttgctca ggcgatcggc
    19801 ggcgttggcg ccggcgctgt ctacggggca agcattggca gcgctttgaa atggttcccg
    19861 gatcgccgcg gcttcgcggc gggcgtcacc gcggcgggtt tcggaatggg ctcggcgctg
    19921 acgatcatcc cgatcgcgtc gattatcgcc aatcagggct tccagcaggc gttcctatat
    19981 ttcggtctgc tacagggaat tgtgctctgc gtttgcgcga ttttcctgaa agctcccgag
    20041 aagattgacg tcacaaaagc cgccgatatg gcggtcgtcg gcgagcggcg gcagtataat
    20101 ccctgggaga tggcgcgcac gcctgtgttc tggcttatgt acgccatgtt cgtcatgatg
    20161 gcggccggcg gcctcatggc gacggcgcaa ctcgggccga tcgcaaagga tttcggcgtc
    20221 gccggcgttc cggtcagcat tctcggattg accttgccgg cgctgacctt cgcgctttcg
    20281 atcgaccgcg tgctcaatgg cctgacgcgt ccctttttcg gatgggtgtc cgacaagatc
    20341 gggcgcgaag tcacgatgtt tatcgccttc gggctggaag ggctggctat tctggcgctc
    20401 agcaaattcg gccacacgcc gggaatgttc gttctgctga ctggccttgt gtttttcgcc
    20461 tggggcgaaa tctacagcct gtttcccgct acttgcgccg acacttttgg cggcaaattc
    20521 gccgcggcca acgccggttt gctctacaca gcgaagggaa cagccgctct gctggttcct
    20581 ttttccagca tgctcaccgc cgcgaccggc agttggca
//
